Biomedical subjects
J D Zaaijman
Publications and source records attributed to J D Zaaijman.
Strange neonatal scalp skin lesions.
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[Premature labor and labor suppressants].
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Group B beta-haemolytic streptococcus and perinatal infections.
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Spontaneous premature rupture of the fetal membranes.
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[Pre-eclampsia, disease of many theories].
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Fetal heart rate changes associated with standard, segmental and modified segmental epidural block.
Three different techniques for epidural block were used and compared in an attempt to lower the incidence of fetal heart deterioration patterns occurring after the block. Segmental epidural block allowed of lower dosages of bupivacaine, but only when the patient knelt on all four was it possible to eliminate post-block fetal heart deterioration completely.
Hypotension after lumbar epidural analgesia.
Despite preloading with fluid, a fall in the mean arterial pressure was recorded in 66% of patients after standard epidural analgesia. In 83% of patients in whom blood pressure fell, hypotension was classified as moderate or severe. In cases of severe hypotension the dermatome level of the block always surpassed T9. The maximal fall in blood pressure always occurred within the first 25 minutes after administration of the local anaesthetic agent.
[Factors determining the rate of weight gain of the human fetus in utero].
A brief review is given of the factors determining the rate of weight gain of the human fetus in utero. A number of genetic, metabolic and environmental factors are outlined. Knowledge of these factors is important in modern obstetric care.
The quantitative effect of lumbar analgesia on uterine work output.
The effect of lumbar epidural analgesia on uterine work output was studied in 36 women during labour. During the first 10 minutes after administration of the local anaesthetic agents there was a 46% loss of uterine activity. In 72% of patients uterine activity returned to normal within 30 minutes. Seventeen per cent of patients required additional oxytocic stimulation.
The effect of lumbar epidural analgesia on the fetal heart.
Fetal heart rate was monitored by continuous cardiotocography in 67 patients who were subjected to standard epidural block. In 43% of cases a deterioration in the fetal heart rate pattern was observed. The abnormal heart rate usually responded to conservative treatment. In 3 cases caesarean section was necessary. The deterioration of the fetal heart rate was usually associated with maternal hypotension.