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Biomedical subjects

J Damas-Mora

Publications and source records attributed to J Damas-Mora.

5 recordsLinked to original sources

Diminished hypercapnic drive in endogenous or severe depression.

Resting breathing rate, resting end-tidal PCO2 and ventilatory response to CO2 were studied in patients with primary depression. Patients tended to breathe faster and showed decreased PECO2 levels when compared with control subjects. Carbon dioxide response was determined using a modification of the rebreathing technique of Read. Endogenous depressives, unlike reactive depressives, tended to give low CO2 responses and low CO2 thresholds. Carbon dioxide responses of patients on admission correlated highly with severity of depression. The modification of the standard rebreathing technique, and the relationship between CO2 response and physical and psychological variables are discussed.

Adult↗

The Charles Bonnet syndrome in perspective.

The clinical condition occurring in the elderly with preserved intellectual functions, characterized by vivid, elaborate and dynamic recurrent visual pseudo-hallucinatory phenomena of a pleasant or neutral nature and often associated with ocular pathology - the Charles Bonnet Syndrome - is described. Its main clinical features are illustrated and the aetiology discussed. Two new cases are presented and areas for future research are outlined.

Age Factors↗

Menstrual respiratory changes and symptoms.

The duration of standardised overbreathing required to produce slow wave activity in the EEG during different phases of the menstrual cycle has been studied, and changes in carbon dioxide sensitivity of the respiratory system. Normal subjects developed slow waves more quickly and had more sensitive CO2 responses during the premenstrual/menstrual phases. This may be a factor contributing to premenstrual tension.

Adult↗