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Biomedical subjects

J David-Chaussé

Publications and source records attributed to J David-Chaussé.

At least 19 recordsLinked to original sources
PubMed1987

[Surveys of the treatment and socio-professional future of patients with spondylarthritis. Our impressions in 1986].

After a brief historical reminder, the authors emphasize the difficulties of such investigations; difficulties of realization, analysis and synthesis since the results depend on ethnic and socio-cultural origins, socio-professional factors, primary or secondary forms or the length of evolution of the disease. From their experience, the authors draw a certain number of figures which they compare to those from other authors, especially concerning factors which aggravate the functional prognosis of the disease, or condition its complications. As for the therapy, considering the divergent opinions expressed about the results obtained with modern treatments, and used for thirty years, the authors have initiated an opinion survey among the members of the FSR (French Society of Rheumatology). The analysis of personal cases, the synthesis of various publications, the results of their survey, lead them to conclude that the problem of the treatment of ankylosing spondylo-arthritis and its professional consequences, is currently still more medico-social than scientific. The picture of rheumatoid pelvispondylitis seems less severe today than before, but it is necessary to have a longer follow-up to evaluate it statistically.

Africa, Northern↗
PubMed1984

[Centrosomatic tuberculous vertebral osteitis. General review apropos of 4 cases].

Defined by the localisation of tuberculous infection in the vertebral body, centrosomatic tuberculous vertebral osteitis, which is rarer than Pott's spondylodiscitis, is more frequently seen in the cases of multifocal tuberculosis occurring preferentially in male black African immigrants approximately 30 years of age. Central area destruction, which has been the initial and pathognomonic radiological sign since its description by Calve and Galland , may progress towards wedging of the vertebral body, and even to its complete disappearance, accompanied by reactive osteocondensation . Infection from this particular localisation of vertebral tuberculosis may spread via arterial branches posterior to the vertebral bodies.

Adult↗
PubMed1983

[The outcome of reactive arthritis].

Cases of reactive arthritis generally have a favourable short-term outcome, within 1 to 6 months in 50 to 70 per cent of cases. The curable nature of the disease and its short clinical course mean that the therapeutic approach should be devoid of risks. Antibiotics, which are necessary for the mucosal lesion, are ineffective in the joint involvement. Non-steroidal anti-inflammatory agents, sometimes in combination with intra-articular steroid injections, seem to be sufficient in the simple forms. In the more chronic, polyarticular forms, gold therapy would appear to be preferable to the use of drugs which act on the immune system. However, the favourable short-term course is overshadowed by the incidence of relapse (30 to 50%), which are sometimes multiple, and by the subsequent development of pelvispondylitis (30% of cases) after an average of about 6 years. Permanent or recurrent peripheral joint manifestations can be seen. The clinical course of these conditions is very similar, whatever the causative agent.

Anti-Inflammatory Agents↗
PubMed1982

[Tolerability of pirprofen during prolonged treatment].

During a non-comparative multicentric study, 70 patients suffering from various rheumatological diseases were treated by pirprofen for an average duration of 32 weeks (from 1 to 121 weeks). The daily dose varied from 400 to 1200 mg. Efficacy was judged good or excellent in 53 of the 70 patients (75%). Side effects, especially digestive, were noted in 27 patients (38%). They only caused discontinuation of treatment in 9 patients (13%). Amongst the 38 side effects, 26 occurred during the first 8 weeks of treatment. Despite the long duration of the treatment, the overall tolerance of pirprofen was good or acceptable in 87,5% of patients. The very high level of compliance in this long-term treatment attests to the good tolerance of pirprofen.

Anti-Inflammatory Agents↗
PubMed1982

[Critical study of patella alta. I. Comparison of results of methods for measuring patellar height in 100 control subjects].

The vertical patellar position is a function of patellar tendon length. Various easily-performed radiological techniques can be used to establish indices which define patellar height. 200 measurements were carried out on 100 control subjects who were free of knee joint pathology, and the various techniques were subsequently compared. Insall's index which is calculated as patellar tendon length over patellar length appears to be the most convenient measurement to use. When it is difficult to precisely determine the patellar tendon's lower insertion on the tuberosity of the tibia, Caton's or Blackburne and Peel's indices are preferable. Blummensaat's line does not seem to be dependable in view of the variations which were observed.

Adolescent↗
PubMed1982

[Critical study of patella alta. II. Patella alta and femoropatellar pathology].

Patella alta is radiologically defined by an Insall index equal to or greater than 1.3. In 50 patients suffering from pain of the femur and patella, roentgenographic studies consisting of a simple profile view and occasionally completed by a view through Smillie's angle with the knee hyperextended, revealed patella alta. The stretching of the patellar tendon is facilitated by excessive tension during growth and by excessively strenuous physical exercises; patella alta can occasionally be complicated by Osgood-Schlatter's or Sinding-Larsen Johansson's disease. Ruptured tendons have occasionally been observed. Genu recurvatum can also lead to patella alta. The joint should be routinely examined for excessive mobility. Patella alta is often associated with various affections of the extensor apparatus of the knee: pathology secondary to injury, external malposition, gonarthrosis, supratrochlear erosions of the femur. The importance of the role of this condition with respect to patellar chondromalacia has been estimated to varying degrees. The diagnosis of patella alta should be considered in all cases of knee pain.

Adolescent↗
PubMed1981

[Articular infections in adults. Peripheral and vertebral involvement with common bacteria and tubercle bacteria].

2,166 cases of joint infection in adults were reviewed during a national inquiry. The peripheral infections due to common germs (1,080 cases) and tubercle bacilli (260 cases) were characterised by their frequency after the age of 60, the role of corticotherapy in onset of the infection and the predominance of staphylococci (60%) in pyogenic infections, the low proportion of deaths (4%) and the necessity of early treatment to observe better functional results. The vertebral lesions due to common bacteria (491 cases) were mainly localised in the lumbar regions (70%) whereas tuberculous infections (335 cases) usually affect the lower dorsal vertebrae (50%). Neurological signs and abscess were more frequent during tuberculous involvement. Needle puncture of the vertebral focus should be recommended owing to its help in etiological diagnosis. A cure was generally obtained without operation in the form of complete or incomplete block, this appearance is, however, less frequent than radiological signs of fixed osteolysis. The mortality is just as low as in peripheral infections.

Adolescent↗
PubMed1980

[Fiessinger-Leroy-Reiter disease seen in a rheumatology unit. Apropos of 71 cases].

71 cases of Reiter's disease have been observed since 1972. After a study of the clinical characteristics of these cases, we report the results of 3 laboratory examinations which, grouped together, facilitate the diagnosis of the complete forms, but, above all, of the incomplete and synovial forms. The search for chlamydia cell inclusions was positive in 80% of cases where carried out. The lymphocyte transformation test with the chlamydia antigen was positive in 72% of cases. The search for HLA B27 was positive in 78% of cases.

Adult↗
PubMed1976

Results of the rectal administration of ketoprofen in fifty-two patients.

The results of a clinical study of ketoprofen suppositories suggest that the drug is effective when given in this way. It is suggested that, in the treatment of inflammatory rheumatic disorders, advantage should be taken of the longer duration of action of ketoprofen suppositories to prescribe their administration early in the morning and before retiring. Local intolerance occurred in only 4 of 52 patients.

Adult↗
PubMed1976

[Atrioventricular blocks and rheumatoid arthritis].

Among 379 hospitalized cases of rheumatoid polyarthritis, 12 auriculo-ventricular blocks were detected between 1965 and 1975. The formation of a complete AV block is usually preceded by a branch block or a first degree block. During the installation of a pacemaker, hypoexcitability was usually noted. Four of the patients died. In the other 8 the evolution has been satisfactory over periods from 6 months to 4 years. Conduction disturbances were found in cases of polyarthritis of 10 years duration on the average. The articular lesions were normally diffuse with considerable lesions detectable radiologically. In many cases the frequency of extra-articular lesions indicated the severity of the rheumatic disease. From the anatomical point of view, histological lesions of rheumatoid polyarthritis were found : granuloma and arteritis in the myocardium. Only 8 authors have previously reported lesions of the donducting vessels at autopsies carried out on rheumatoid polyarthritis cases who had presented AV blocks. Except for Thery's case related to amylosis of the nodal tissue, rheumatoid granulomas occupied the whole or part of the nodal tissue. In elderly subjects suffering from rheumatoid arthritis, it was difficult to establish a strictly rheumatoid origin for the AV blocks observed, unless specific granulomas were discovered anatomically in the nodal tissue.

Adult↗
PubMed1976

[Multicentric reticulohistiocytosis (lipoid dermato-arthritis). Apropos of a case with fatal outcome].

The authors report the case of a 37-year-old man affected by a seronegative polyarthritis associated at first with erythroderma and then with cutaneous and subcutaneous papulo-nodular structures and a xanthomatous eryption. Histological examination of the cutaneous nodules and of the synovial membrane confirmed the diagnosis of multicentred reticulohistiocytosis by showing the presence of lipid infiltrates in the histiocyte cells and of multinucleate giant cells. A study of the ultrastructure of the histiocytes revealed the presence of numerous intracytoplasmic vacuoles. In spite of antimalaria treatment, with cortisone and then with immuno-depressants, the outcome was fatal with a picture of acute reticulosis and neurological disorders. In discussing this case, the authors also make a general review of the subject.

Adult↗