The science and practice of John Patrick: the connection between Oxford, London and Maastricht.
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Animals↗
Biomedical subjects
J De Haan
Publications and source records attributed to J De Haan.
High-field magnetic resonance imaging of Wilson's disease.
A single case of Wilson's hepatolenticular degeneration was imaged by computed tomography and magnetic resonance (1.5 Tesla). Findings included generalized cerebral atrophy seen both on computed tomography and magnetic resonance images. T1-weighted images revealed a slight symmetric hypointensity in the lentiform nuclei and thalamus. T2-weighted images demonstrated marked symmetric hypointensity in the lentiform nuclei. These hypointensities are ascribed to the deposition of intracellular hemosiderin (and perhaps copper), which produce heterogeneous magnetic susceptibility and preferential T2-proton relaxation. Areas of increased signal activity on T2-weighted images were also seen in areas of presumed demyelination known to occur in Wilson's disease.
Adolescent↗
Making evaluation systems cost-effective.
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Colorado↗