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Biomedical subjects

J Dehenry

Publications and source records attributed to J Dehenry.

2 recordsLinked to original sources
PubMed1987

[A technic for human basophil degranulation].

We had studied the human basophil degranulation test (HBDT) in 26 cases of allergic patients with drugs (penicillin, erythromycin, josamycin) one month after their anaphylactic reaction. This test was negative in 7 cases on 8 for penicillin, positive in 8 cases on 10 for erythromycin and in 6 cases on 8 for josamycin. The failure of this test with penicillin can be explained by a sensitization to a metabolic penicillin product or to the complex hapten-carrier.

Basophils↗
PubMed1987

[Value of cellular immunity tests (lymphocyte transformation test and leukocyte migration test) in the detection of sensitivity to drugs].

We studied degranulation of human basophils (HBDT), lymphoblast transformation and leucocyte migration in 8 cases of patients who were sensitive to penicillin (type 1 hypersensitization of the Gell and Coombes classification). The HBDT was negative in 7 of the cases, whilst the lymphoblast transformation and leucocyte migration tests were positive in 6 cases and negative in 2. These latter tests are more efficient than HBDT in the detection of human sensitization to penicillin.

Cell Migration Inhibition↗