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Biomedical subjects

J Delaire

Publications and source records attributed to J Delaire.

At least 19 recordsLinked to original sources
PubMed1995

Primary closure of the cleft alveolus: a functional approach.

The growth and development of the premaxilla in both normal and cleft lip and palate subjects is described and its relevance in surgery of the cleft alveolus discussed. Embryologically, the cleft alveolus results from failure of fusion of the median nasal and maxillary processes. Consequently, ossification centres in the premaxilla and maxilla cannot migrate and unite such that normal growth and development in the territory of the premaxillary-maxillary suture cannot occur. Functional repair of the cleft lip and soft palate encourages spontaneous alignment of the alveolar segments, facilitating the introduction of vascularized periosteum across the bony defect by gingivoperiosteoplasty. Early reconstruction in the region of the premaxillary-maxillary suture encourages a more normal development of the alveolus, particularly in the bilateral cleft subject.

Alveolar Process↗
PubMed1995

Treatment of the craniofacial complications of Beckwith-Wiedemann syndrome.

Variable degrees of macroglossia have been noted in patients with Beckwith-Wiedemann syndrome. Past studies have shown that a major effect of the macroglossia is protrusion of dentoalveolar structures, resulting in an anterior open bite and a prognathic mandibular appearance secondary to an abnormally obtuse gonial angle and increased effective mandibular length. In our series of 11 Beckwith-Wiedemann syndrome patients we have observed that early correction of the macroglossia by means of partial glossectomy has resulted in decreased anterior open bite and mandibular prognathism as compared with patients managed conservatively.

Beckwith-Wiedemann Syndrome↗
PubMed1994

Histochemical analysis of cleft palate muscle.

Research has clarified the abnormal insertions and orientations of the involved musculature in cleft palate. However, little is known about the physiologic aspects of these muscles, specifically from a histochemical perspective. In this study, 30 muscle specimens were removed from the palatal cleft margin in patients undergoing primary palatoplasty. Nine patients had combined cleft lip and palate deformity, and seven had an isolated cleft palate. Biopsies were taken from the area of the musculus uvulus in all specimens and examined by histochemical techniques. The percentage of type 1 and type 2 fibers was different in isolated cleft palate as compared with cleft lip and palate specimens, being, respectively, 56.7 percent type 1 and 43.3 percent type 2 and 62.0 percent type 1 and 38.0 percent type 2 fibers. This is the opposite ratio from other facial muscles but is in line with the literature regarding normal palatal muscle. Isolated cleft palate muscle fibers also were minimally decreased in diameter as compared with normal facial muscle. Fiber diameters of the combined cleft lip and palate muscles were severely decreased in size compared with those muscles found in the cleft lip. Abnormal mitochondrial accumulations also were found in cleft lip and palate muscle specimens but not in isolated cleft palate muscle specimens. We consider the decrease in muscle diameter found in isolated cleft palate to be secondary to functional atrophy, while that in the cleft lip and palate specimens is secondary to a primary hypoplasia together with a functional atrophy.(ABSTRACT TRUNCATED AT 250 WORDS)

Biopsy↗
PubMed1993

Functional primary closure of cleft lip.

A technique of primary closure of the cleft lip is described. It is based on a complete understanding of the anatomy of the entire facial musculature such that it can be restored to normality and so encourage normal function and development.

Cleft Lip↗
PubMed1992

Facial balance in cleft lip and palate. I. Normal development and cleft palate.

A full understanding of balanced facial growth, based on a complete knowledge of the anatomy and physiology of the region, is essential if cleft lip and palate is to be treated successfully. The cleft abnormality is the cause of underdevelopment and subsequent loss of function. Cleft surgery must aim to restore normal anatomy and physiology with emphasis on muscle reconstruction of the lip and soft palate if normal facial development is to be achieved.

Adult↗
PubMed1992

Facial balance in cleft lip and palate. II. Cleft lip and palate and secondary deformities.

The cleft abnormality is the cause of underdevelopment and subsequent loss of function. Primary cleft surgery and surgery to correct the secondary deformities of previous non-functional repair should aim to restore normal anatomy and physiology, with an emphasis on muscle reconstruction of the lip and soft palate if normal facial development is to be encouraged.

Cleft Lip↗
PubMed1991

[Medicolegal considerations. Apropos of tooth germ transplantation between 2 twins].

With regard to medicolegal problems, semantics are of considerable importance: indeed, depending on whether we call grafting or transplantation of an organ the operation that takes a living organ to reimplant it in the same person or the operation that takes a living organ from a donor to reimplant it in a recipient, the issues raised are completely different. The transposition of a dental organ does not raise any particular problems apart from the technical requirements to be met; there is no special problem of prevention or ethics to be taken into consideration. The problem is a completely different one when it means taking a living organ from a living or dead subject and reimplanting it in another subject. All measures decreed from the point of view of law and regulations that are dictated by considerations of prevention and ethics must then be strictly applied.

Expert Testimony↗
PubMed1991

[Binder's syndrome (maxillo-nasal dysostosis) and associated orthopedic malformations].

The authors refer to cases of associated orthopedic malformations reported in 17 patients with Binder's syndrome. Aside from already known anomalies of the cervical spine detected in 58.8% of cases, finger malformations are found in one third of single X-chromosome carriers (boys or Turner's syndrome). This calls for studying these malformations in parallel with X-linked minor isolated recessive chondrodystrophy.

Abnormalities, Multiple↗
PubMed1991

[A new case of adenomatoid odontogenic tumor].

We have reported a new case of adenomatoid odontogenic tumour, treated as is classic, by simple enucleation that is the selected treatment. This lesion is, in fact, a malformation and not a variety of ameloblastoma as some denominations (ameloblastic adenomatoid tumour, adenoameloblastoma) could make to think.

Adolescent↗
PubMed1990

[Prognostic and therapeutic aspects of lympho-epithelial lesions of the parotid. Apropos of 8 cases].

The so-called benign lympho-epithelial lesion (BLEL) of the parotid is a rare condition. Its diagnosis is based on histology. For a long time there have been problems with its classification and prognosis: classification since certain cases may be classified as Sjögren's syndrome or as a precursor of the latter, prognosis there may be recurrence, contralateral involvement or progression to non-hodgkin's lymphoma. The authors discuss these factors in 8 cases and propose total parotidectomy with facial nerve preservation as the treatment of choice.

Adult↗
PubMed1990

[The role of the condyle in the growth of the mandible and in facial balance].

The condyle is not responsible for the growth of the body of the mandible, as the latter does not extend in length caudally at the expense of the ascending rami (through the classical relocation phenomenon), but does so deep to these, at the level of the lower insertions of the sphenomandibular ligaments (i.e., from the inlet inner border of the inferior dental canals). Philogenetically and ontogenetically, its appearance reflects the adaptation of the mandible of mammals to the morphologic and functional changes that took place in their cephalic skeleton (more erect posture, more vigorous mastication). Its chief role in man is to stabilize the mandibular body and to allow it to be properly mobilized, although contributing also to its forward and downward movements (namely in its posterior aspect). As such, it plays an active role in mandibular growth, and this role varies according to the primary "potential" of the condylar cartilage. Such primary-type potential for condylar growth may be adequately assessed by studying the shape of the mandible, as well as through an analysis of craniofacial architecture. Most of the conventional diagrams depicting mandibular growth are defective. Another figurative system has to be innovated, that will differentiate each skeletal unit--body, condyle, coronoid process, angle, alveolodental arch--, the sum of which confers the shape, the size, and the multiple variations to the mandible as a whole.

Animals↗
PubMed1990

[Labioglossopexy in Pierre Robin syndrome. Our experiences apropos of 70 cases].

Pierre Robin syndrome is typically characterized by glossoptosis and retrognathia associated with cleft palate, respiratory and deglutition disturbances. Two morphological tendencies arise out of this 70-patient series, 50 of whom were managed with the same therapeutical regimen, which included labioglossopexy and was associated with only one case of death: "deforming" type Pierre Robin syndrome most commonly follows a favorable course with respect to both function and facial deformations, provided labioglossopexy is carried out sufficiently early. Indeed, this surgical operation allows for prompt restoration of normal function, thereby limiting the dysfunction-deformation vicious circle. This form of Pierre Robin syndrome may find its origin in the embryo's abnormal amniotic environment. "Malformation"-associated Pierre Robin syndrome often presents with combined anomalies, respiratory disturbances that may evolve into severe airway problems, impaired deglutition and abnormal brain development; in most cases, labioglossopexy will dramatically improve the immediate state of the child, although long-term prognosis as regards malformation is rather guarded.

Adolescent↗
PubMed1990

[The place of mandibular condylectomy in surgery of temporomandibular joint dysfunction].

Mandibular condylectomy is one of the methods to which one must sometimes resort when treating temporomandibular joint dysfunction. As emphasized by Merville, this is the conventional method used whenever dealing with condylar hypertrophy , as well as in certain grade-III cases with deep bite. However, another interesting indication for it is the horizontal configuration of the occlusal plane, leading to pain and/or luxation. This type of surgical joint operation presents no risk whatsoever, provided the meniscus is respected.

Humans↗
PubMed1989

[Changes in the posterior vertical dimension of the face. Etiopathogenic factors, architectural criteria and therapeutic aspects].

The ramus of the mandible appears with the cephalic hominisation phenomenous during phylogenesis and determines the vertical posterior height of the face. Among the three skeletal units that form it, the condylar one is responsible of this height and of the level of the posterior part of the occlusal plane. So, all congenital, constitutional or acquired diseases concerning this unit, give a change of the vertical posterior height of the face. The excess troubles ar essentially represented by the condylar hyperplasia, usually unilateral and treated by condylectomy. The vertical posterior insufficiency may be unilateral or bilateral. The former looks like a mandibular asymmetry whereas the latter looks like an anterior vertical excess with or without a Class II malocclusion. If the condyle is absent or T.M.J. destroyed like in ankylosis, the authors use the costo-chondral graft to repair it. But in condylar hypoplasia, they use a vertical osteotomy of the ramus for lengthening the ramus. The three-dimensional architectural analysis is very useful for studying the vertical posterior height of the face and his changes.

Humans↗