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J Derka

Publications and source records attributed to J Derka.

5 recordsLinked to original sources

[Evaluation of synthetic activity of lymphocyte nucleoli and phagocytic activity in peripheral blood leukocytes in heifers after infection with infectious bovine rhinotracheitis virus].

The biosynthetic activity of the nucleoli of peripheral blood lymphocytes in calves, and the proportion of lymphocytes with the micronucleoli, with compact and ring-shaped nucleoli, were evaluated after experimental intranasal and intratracheal infections with the infectious bovine rhinotracheitis (IBR) virus. IBR virus belongs to the group of herpes viruses, the control of which is dominated by cellular immunity. The results are compared with the values for phagocytizing neutrophils, phagocytic activity and phagocytic index of the leucocytes of peripheral blood and with some basic haematological data.

Animals↗

Syngeneic lines of chickens. VI. Immunoglobulin allotypes.

In the course of study of alloantigenic immunoglobulin polymorphisms in 10 inbred chicken lines we detected 7 IgG allotypic specificities and 3 IgM allotypes. All birds in a given line possessed a unique combination of several IgG alloantigenic specificities (forming the phenogroup) which is presumably controlled by one allele at the locus designated a. We found five such phenogroups and five corresponding alleles (allele ac in three C lines, aI in three I lines, aW in two W lines, aM in line M, and aF in line F) in inbred lines tested. Furthermore, it could be inferred that each IgM allotype is the marker of one allele at the locus D. The distribution of these alleles among inbred lines was determined (allele dC was present in lines C and F, allele dI in lines I and M, and allele dW in lines W). A 2.8% recombination between loci a and d that are linked was found. The study of linkage between immunoglobulin allotype loci and blood group loci A, E, B, C, D, and I revealed no deviation from independent assortment of thse loci.

Animals↗

[Induction of components of the natural precipitation system (GANS) and another antibody after alloimmunization with serum or egg yolk in fowl].

Detailed analysis was performed in 17 selected serums obtained through alloimmunization of 64 receptors (cocks and hens, WP X RIR hybrids) of type 0 in the GANS system. The serum or egg yolk from hens of type A or B in the GANS system, used for immunization, was applied in five intramuscular injections with or without using Freund's complete adjuvant. It was found out that substance A GANS was present in 16 serums of the total number of those which were examined, so that in the receptors the application of serum or yolk changed the type of the GANS system from original 0 into type A, irrespective of the type of donor. Further, seven serums were found to contain another antibody, reacting in precipitation with the serum fraction which is only present in laying hens and probably has not the character of an allotype.

Animals↗