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Biomedical subjects

J Dimitrijević

Publications and source records attributed to J Dimitrijević.

At least 19 recordsLinked to original sources

Multifactorial analysis in the prognosis of ischemic cerebrovascular accidents.

An attempt to determine the prognosis of an individual patient with ischemic cerebrovascular accident means an attempt to take into consideration several parameters at the same time. Discrimination analysis was done as a retrospective study of 316 patients, who were followed from the moment of accident (admitted to the clinic within 24 hours), to four weeks after the accident. Nineteen parameters were determined by degree and correlated with the outcome through statistical significance of a single parameter p less than 0.05). After that, the parameters with statistical significance (age, state of consciousness, severity of motor deficit, previous episodes of cerebrovascular disease, Babinski sign, conjugate deviation of eyes, the way of onset of the disease) were used in a multifactorial analysis. The first analysis referred to the prognosis of survival (76 patients died, 240 patients survived). It was shown that the chosen parameters were satisfactory, since in 87% of cases they divided groups in an appropriate way, i.e. the group of deceased patients amounted to 76% and for the group of survived patients the score amounted to 90%. The second analysis referred only to patients who survived, with the aim to determine the probability of the quality outcome prognosis. It was shown that the same parameters were less reliable and the classification into two groups was done in 76% of cases (for--no deficit or small deficit group--in 73% of cases and for--severe deficit group--in 84% of cases.

Brain Ischemia

[The Miller-Fisher syndrome (clinical report)].

The authors present a case report of two female patients, aged 16 and 33. Both patients had the same sudden onset of illness, with diplopia and nystagmus and very severe ataxia. The younger patient had absent tendon reflex, while the older one had the tendon reflex preserved. The younger patient had the triparesis present, both patients had no sphincter disorders. They did not have sensibility disturbances, except that the younger patient had hypesthesia of the soft palate (the motor function was preserved). The first patient was somnolent at the beginning. The clinical course being favourable, the younger patient recovered faster than the older one. Electoencephalogram was normal in both patients. CT of the brain was changed at one moment, locking like inflammatory changes. CSF of the younger patient, done twice, was normal. Serologic findings on viruses were normal. Electromyography in both patients showed, beside good motor velocity, the marked sensory velocity which recovered at the control check-ups. The authors present these two cases and they consider the differential-diagnostic difficulties of Fisher's syndrome compared to "brain stem encephalitis".

Adolescent

[Takayasu's disease and cerebromeningeal hemorrhage].

A 53-old-woman with both Takayasu disease and intracerebral hemorrhage is reported. Non-specific aorto-arteritis was acquired, while aneurysm on arteria cerebri media is probably of congenital origin. The association of these two syndromes is, judging by this facts, accidental. Nevertheless, it should be taken into consideration than panarteritis had a significant role in formation of aneurysm and favored the appearance of hemorrhage.

Aortic Arch Syndromes