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Biomedical subjects

J Djulepa

Publications and source records attributed to J Djulepa.

13 recordsLinked to original sources
PubMed1983

Urethrotomy technique in urethral strictures: 6-year results.

Our urethrotomy technique for strictures during the last 6 years is analyzed. Each stricture was widened radially over the entire circumference with incisions made close together. In this way a short or moderately long stricture can be eliminated completely in 1 session. For long and multiple strictures only the most distal portion was incised as far as possible. Then, after 2 to 3 weeks, control urethroscopy was done and the remaining stricture subsequently was incised without difficulty using the same technique. Urethrotomy was done with the patient under local anesthesia with mepivacaine because of the better field of view. Instillagel was not used. This technique does not require any followup treatment of the urethra. Since no indwelling catheter is needed foreign body urethritis, which can be the cause of stricture recurrences, is avoided. The postoperative course is shortened greatly. There is greater freedom from complications and the chances of healing are improved. The operation can be performed rapidly and the burden for the patient is slight. Secondary injuries are rare. Sessions can be repeated without complications. Potency is not endangered. This operation can be done on an ambulatory patient with any type of stricture. The late results in 202 patients with simple and complicated strictures who underwent this technique were evaluated. Most strictures were incised in 2 or 3 sessions, which gave the best results. A few complicated callous strictures that had been treated for years with bougienage were incised in 4 or 5 sessions. The over-all success rate of the late results is more than 80 per cent.

Humans↗
PubMed1982

[Etiology of hematuria from the urologic viewpoint].

The importance of hematuria in urology was analyzed with special consideration of microhematuria. It is especially emphasized that in microhematuria as in marcrohematuria a thorough urological diagnosis must follow in order to detect the source of bleeding with certainty and thus to be able to decide on further therapy. In most of the cases, it was not particularly difficult to localize the source of bleeding in the macrohematuria, in contrast to microhematuria in which a precise source of bleeding can be established only in less than 10%. Microhematuria gives rise to particular problems in cancer prevention in men and women; these not uncommonly lead to "overdiagnosis". The most serious cause of microhematuria are tumors of the kidney and the urinary tract. Patients are often "treated" by the general doctor without certain exclusion of the presence of a tumor. This leads to a delay in diagnosis in painless hematurias. It is known from the literature that despite massive hematuria on average three months pass until the patient visits an urologist. The urologist therefore often diagnoses advanced urogenital tumors which can no longer be successfully treated.

Aged↗
PubMed1977

[The distribution of antibiotics in extravascular renal tissue during experimental pyelonephritis of dogs (author's transl)].

For the success of an antibiotic therapy in pyelonephritis the concentration of antibiotics attainable in the kidney tissue is of extreme importance. Therefore in dogs, besides serum level and urin level a tissue level was defined after a single dose of gentamycin and cefazolin. While gentamycin is highly concentrated in the kidney, which is indeed more in a state of shock than health, Cefalozin is being excreted, after initially high values, excreted in a course approximately parallel to the blood level curve, within 5 h down to concentrations between 1 mcg/ml and 4 mcg/ml. The level of the tissue in the cortex of healthy kidneys and infected kidneys without additional damage by a ureter ligature averaged about 40% less than the serum level. The tissue level of kidneys infected by the additional damage of a ureter ligature and with signs of a pyelonephritis was extremely lower and reached occasionally hardly 20% of the serum level. Attention is also called to the consequence of these results for the therapy of the pyelonephritis.

Animals↗