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Biomedical subjects

J Dolgos

Publications and source records attributed to J Dolgos.

3 recordsLinked to original sources
PubMed1993

[Smoldering myeloma].

The authors present the history of a 74 year old woman. The patient was observed from 1972. Initially the bone marrow and serum protein dischanges were identical to multiple myeloma, therefore she was treated with melphalan-prednisolone regimen for one year. She was symptom free for 12 years with none of any treatment. Her bone marrow picture and serum protein aberrations were stabil. In 1985, the clinical signs and laboratory parameters of multiple myeloma arised. Major clinical symptoms, myelomatous bone lesions were detectable and the monoclonal protein level increased. In activation period repeated local irradiation and VCMP and VACP polychemotherapy was performed. Her history was typical to smoldering myeloma. The presentation of that disease is not available in Hungarian literature. The authors present the criteria of diagnosis, the therapeutic possibilities and the differential diagnosis of benign and malignant gammopathies.

Aged↗
PubMed1991

[Hyperparathyroidism simulating severe hypercalcemia syndrome].

The case history of a 65 year old female patient has been reported here by the authors. The patient was admitted to the Intensive Therapy Unit owing to her repeated heart pain. Later she was transferred to the Department of Medicine to establish the exact diagnosis. Prepyloric ulcer and hypertension were occurred in her history. The symptoms of her preceding as well as her recent illness were: pain in epigastric field, nausea, adynamia, weakness, polyuria, significant loss of weight, somnolence and the shortened Q--T time in electrocardiogram related to hypercalcemia syndrome. The calcium value in blood proved to be at critically high level from time to time. The possibility of the secondary hypercalcemic state was excluded by sonographic examination and the elevated level of parathormone in blood established the diagnosis of the hyperparathyroidism. The surgical resection of parathyroidic adenoma yielded a complete recovery of the patient. The authors call the attention to the significance of the clinical signs in the diagnosis of the disease.

Aged↗