Biomedical subjects

J Donát

Publications and source records attributed to J Donát.

At least 19 recordsLinked to original sources

PubMed1991

[Electroanalgesia in programmed delivery].

The influence of electroanalgesia on the uterus activity, delivery duration, pH, P02, PCO2, Hb02, BE, sodium and potassium values in venous and arterial umbilical blood as well as in venous mother's blood has been evaluated. The investigated total was composed of 31 pregnancies, in 18 of them the delivery was backed with electroanalgesia, and the remainder of 13 represented a control group. No statistical significance has been evaluated as to the duration of delivery in both groups. The positive finding resides in significantly higher Hb02 and lower Be umbilical blood values in a group with applied electroanalgesia. No significant differences were found out in the rest of either the indices of respiratory foetal metabolism or sodium and potassium values in contrast of control group.

Analgesia, Obstetrical↗

PubMed1991

[Precanceroses and endometrial carcinoma].

Precanceroses and early screening of endometrial carcinomas are reviewed. Measures are evaluated on how to prevent this malignancy with administration of gestagens in hyperplastical endometrial changes in climacteric conditions and manifestations of endometrial estrogenization in postmenopause. On the basis of clinical, laboratory and histological investigations, the total of 31 female subjects with dysfunctional bleeding was given medroxyprogesterone acetate (Provera Upjohn tbl.) in 10 mg daily doses for up to 10-13 days cyclically prior to the onset of menopause. Under the mentioned treatment any of them experienced the rebleed, and no endometrial carcinoma had been diagnosed with control vacuum curettage within one year of observation. In a total of 196 women operated on to endometrial carcinoma, the occurrence of risk-factors for the development of mentioned tumour (obesity, late menopause, i.e. menopause after 50 years of age, sterility and dysfunctional bleeding backed with anovulation, long-term estrogen administration, feminizing ovarian tumours, liver diseases, glycide metabolic disorders and hypertension) was evaluated. The present work was aimed on the screening of asymptomatic group of women. Two important signs (obesity and late menopause) were invariably determined with the addition of any other risk factor. Mentioned women are supposed to undergo regular yearly histological investigation of endometrium. Of most benefit the vacuum curettage is believed by authors as a result of comparing the validation of cytological and histological methods in order of early evidence.

Adult↗

PubMed1990

[The effect of hormone therapy on the lipid spectrum in postmenopausal women].

In a group of 92 postmenopausal women with climacteric and postcastration syndrome the relationship between different types of hormonal therapy and changes of indicators of the lipid metabolism was investigated. Before onset of treatment and after three weeks of treatment the authors assessed total cholesterol, beta-lipoproteins, triglycerides, HDL, LDL and plasma concentrations of oestrone and 17-beta-oestradiol. A significant rise of both oestrogens was recorded in a group treated with Presomen tablets and Folovirin inj. In the lipoprotein fractions only beta-lipoproteins rose significantly during administration of Mestranol tabl. and Provera tabl. The investigation is the beginning of a prospective study concerned with the possibility to influence one of the risk factors participating in the development of arteriosclerosis.

Adult↗

PubMed1990