PubMed Health⌕ Search

Biomedical subjects

J Dubuisson

Publications and source records attributed to J Dubuisson.

57 records · Page 4Linked to original sources

[Virus carriers: analysis of states of equilibrium between the virus and its host].

The various mechanisms of virus persistence are described. Four kinds of virus persistence are presented, depending on their epidemiological significance, persistence associated with continuous multiplication and transmission (feline calicivirus, calf rotavirus); persistence associated with continuous multiplication but discontinuous transmission (equine infectious anemia retrovirus); persistence with continuous multiplication associated with immunotolerance (feline leukaemia retrovirus; mucosal disease pestivirus); latent carrier state with discontinuous transmission (feline and pigeon herpesvirus; infectious bovine rhinotracheitis herpesvirus). The classification of these kinds of virus persistence is based upon their epidemiological significance, even if the mechanisms allowing the persistence are completely different.

Animals↗

A monoclonal ELISA for bovine viral diarrhoea pestivirus antigen detection in persistently infected cattle.

Detection of cattle persistently infected with bovine viral diarrhoea virus (BVDV) is crucial to controlling mucosal disease. A sandwich enzyme-linked immunosorbent assay (ELISA) using monoclonal antibodies raised against the 48-kDa glycoprotein and the 120/80-kDa protein was developed for detecting antigens in leucocytes of 3 persistently BVDV-infected calves. The test is simple, sensitive and rapid. Moreover the same ELISA was able to recognise Belgian field isolates of BVDV. These results show that the test can be applied in the field.

Animals↗