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J Duker

Publications and source records attributed to J Duker.

2 recordsLinked to original sources

Swallowing and speech function after intraoral soft tissue reconstruction with lateral upper arm free flap and radial forearm free flap.

Swallowing, speech, and morbidity were assessed postoperatively in 25 patients, 18 of whom had had intraoral defects reconstructed by lateral upper arm free flaps (LUFF) and 7 by radial forearm free flaps (RFFF). Video fluoroscopy was used to assess swallowing, the Freiburger audiometric test to assess speech; and measurement of arm circumference to assess donor site morbidity. A questionnaire was used to evaluate swallowing, speech, and donor site morbidity subjectively. The degree of impairment in swallowing depended on the site of resection. Anterior and posterior resections affected swallowing more than lateral resections. Anterior resection and the use of LUFFs reduced intelligibility. There was no significant difference in impairment between LUFF and RFFF. We conclude that the LUFFs are superior to RFFFs because they can be closed primary and the incidence of donor site morbidity is slight.

Adult↗

Modeling carbon monoxide uptake during work.

Acute carbon monoxide poisoning is the result of a diminished capacity of the blood to transport oxygen and sustain a level of metabolic activity. The diminished capacity is expressed in terms of the carboxyhemoglobin (COHb) level in the blood which is dependent upon the concentration of CO in the inhaled air. The rate of CO uptake or elimination is dependent upon the concentration of CO in the air as well as pulmonary diffusion capacity and alveolar ventilation which change with different metabolic rates. Coburn, Forster and Kane (CFK) developed a mathematical model to describe the uptake and elimination kinetics of CO in sedentary individuals. The CFK model was used in a mathematical simulation of CO uptake and elimination where the independent variables were inhaled CO concentration and metabolic rate. The metabolic rate was used to specify pulmonary diffusing capacity and alveolar ventilation. As the level of COHb increased the metabolic rate was decreased to a level compatible with the impaired oxygen transport. A physical fatigue limit was also included. The theoretical model was used to simulate conditions beyond the range of exposures permissible under experimental laboratory conditions.

Carbon Monoxide↗