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Biomedical subjects

J Dyckman

Publications and source records attributed to J Dyckman.

12 recordsLinked to original sources
PubMed1995

Integrating self and system: an empty intersection?

Synthesizing individual and family therapies can founder if the underlying epistemological assumptions concerning "what is self" are not taken into account. Most individual therapies assume self "really" exists as a relatively stable internal entity, the repository of residues of experience where traits, memories, et cetera are organized via internal schemas. Such a view tends to treat self as a thing, and implies that psychological problems are the result of internal deficits or conflicts; this can lead to difficulties in therapy. In contrast, ecosystemic views employ constructivist and contextualist approaches that are more fluid. However, by basing autopoetic self-organization in language, ecosystemic epistemology still separates subject from object. Adopting a perspective in which self has no fixed, distinguishing characteristics can resolve many difficulties and create a dimensionless point where self and system, individual and family, therapist and client can meet without hindrance.

Family Therapy↗
PubMed1979

Primary osteogenic sarcoma of the heart.

The clinical course of a 17-year-old boy with primary osteogenic sarcoma of the left atrium with partial obstruction of the mitral valve and the right pulmonary veins is described. After operative removal of the tumor, echocardiography documented its rapid recurrence. Despite two subsequent open-heart operations and adjuvant chemotherapy and radiotherapy, the patient died twenty-one months after the initial symptoms. Previous reports of such tumors are reviewed, and technical difficulties of removal are discussed.

Adolescent↗
PubMed1978

Failure of Dacron prostheses caused by structural defect.

Intrinsic prosthetic failure is quite uncommon since the advent of Dacron prostheses. Only 24 cases of arterial prosthetic failure have been described in the literature. Our experience consists of two additional failures of knitted Dacron prostheses. The first patient developed aortojejunal fistula due to a defect of the aortic prosthesis 6 years after resection and replacement of an abdominal aortic aneurysm. The analysis of the graft revealed a defect in the form of a dropped stitch, which caused a weak spot where the prosthesis was able to be torn apart longitudinally. The second patient had femoropopliteal bypass and 6 years later developed degeneration with aneurysmal formation of the entire length of the prosthesis. Optical microscopy of this prosthesis exhibited mostly transverse failures which were coincident with valleys of the corrugated prosthesis. This was indicative of a defect that rendered the corrugation root too weak to withstand normal arterial pressures. This presentation emphasizes the seldom and serious complication of prosthetic failure due to defect of the prosthetic material. Details of scanning electron microscopy of the prosthesis, clinical presentation, angiography, and pathological findings with treatment also are discussed.

Aorta, Abdominal↗
PubMed1976

Effect of prolactin on maintenance of prelactating human mammary gland in vitro.

Human mammary tissue from a female at the end of the second trimester of pregnancy was studied in organ culture in a chemically defined medium. Sampling was carried out at 1, 2 and 3 weeks. Without hormones, there was nearly total lobuloalveolar degeneration in all specimens at all times. Addition of insulin, hydrocortisone and ovine prolactin, in combination at a concentration of 5 mug per ml each, did not affect the extent of degeneration. Raising the concentration of prolactin to 50 mug per ml resulted in greatly improved lobulo-alveolar maintenance in all specimens and continued epithelial cell DNA synthesis for up to 3 weeks in vitro.

Breast↗
PubMedDate not supplied

Influence of depigmenting chemical agents on hair and skin color in yellow (pheomelanic) and black (eumelanic) mice.

Topical applications of monobenzylether of hydroquinone (MBEH) or intraperitoneal injections of phenol induced graying of hair in eumelanic mice but had little effect on hair color in pheomelanic mice. Amcinonide, an anti-inflammatory agent, elicited whitening of a few hairs in both pheomelanic and eumelanic mice. In phenol-treated eumelanic mice, damaged follicular melanocytes were uprooted from hair bulbs and incorporated into the developing hair. The fate of follicular melanocytes in MBEH- or amcinonide-treated mice was not determined since hair growth and graying were more variable than in phenol-treated mice. In contrast to the susceptibility of eumelanic hair follicles to depigmentation by phenol or MBEH, the tail skin of eumelanic or pheomelanic mice was not depigmented by these agents. Overall, during the 3 week period of treatment that was sufficient for phenol or MBEH to elicit graying of hair, epidermal melanocytes of the tails of eumelanic or pheomelanic mice either failed to respond (phenol) or were stimulated in their "proliferative" and melanogenic activity (MBEH). In contrast, amcinonide brought about a marked reduction in the numbers of DOPA-positive epidermal melanocytes inhabiting the tails of eumelanic or pheomelanic mice. Amcinonide exerted a deleterious influence on the structure and function of tail epidermis. Its actions were partly reversed by simultaneous treatment with MBEH but not with prostaglandin (PGE2).

Administration, Topical↗