Biomedical subjects
Publications and source records attributed to J E Bader.
A new method has been developed to synthesize fluorescein labeled peptides, compounds of increasing importance in bioorganic chemistry, cell biology, pharmacology, drug targeting and medicinal chemistry. We show, that 4(5)-carboxyfluorescein is much more efficient than the hitherto predominantly utilized reagents 4(5)-carboxyfluorescein-N-succinimidylester and 4(5)-fluoresceinisothiocyanate.
BACKGROUND: As clinicians, adult children of aging parents, taxpayers, and future retirees, optometrists have multiple reasons for wanting to know more about aging and for wanting to communicate better with older people. METHODS: Fundamental principles emerging from gerontological and geriatrics research are reviewed. Suggestions are offered for improving clinical approaches and practice settings. RESULTS: Population heterogeneity is the rule with aging due to sociocultural as well as biophysiological changes. Follow through with treatment regimens depends on the availability of financial and human resources and on what else is going on with the older patient at the time. CONCLUSIONS: Diseases should be treated at all ages. Particular attention should be devoted to medications management, to compensating environmentally for normal age changes in sensory functioning, and to avoiding iatrogenic consequences of treatment.
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People of all ages hold aging-related attitudes. Even very young children recognize age differences and evidence attitudes that appear to be generation-specific. Since attitudes presumably affect behavior and since long life has recently become the rule rather than the exception, interaction with old persons and personal attitudes toward growing old may well be influenced by one's general aging-related attitudes. The availability, accessibility, adequacy, and acceptability of human services intended for use by old persons are also influenced by the attitudes of younger persons. The aging-related attitudes of decision-makers, services personnel, and tax-payers are particularly important in this regard. Much of the U.S. research literature on aging-related attitudes will be reviewed here. Only the highlights of individual articles will be presented, however. Therefore, this paper might best be regarded as a reference to the literature rather than as a restatement of it.
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Recent respite care research is reviewed, advantages and disadvantages of respite- and home-based care are presented, and some recommendations are introduced. It may be more cost-effective to invest in caregivers' physical, financial, and emotional well-being than to provide the care required when caregivers become "patients." Practical and policy issues are raised regarding the desirability of investment in respite care.
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