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Biomedical subjects

J E Bowers

Publications and source records attributed to J E Bowers.

8 recordsLinked to original sources
PubMed1989

Evaluation of a chairside gingival protease test for use in periodontal diagnosis.

Collagen degradation is a major factor in the destruction of diseased periodontal tissues. Evidence from several investigations indicates that this connective tissue breakdown process may be associated with elevated levels of proteolytic activity in gingival crevicular fluid. A rapid, chairside assay for neutral proteases in biological fluids was evaluated clinically for reproducibility and an indicator of periodontal disease status. This colorimetric test is based on the use of an insoluble, covalently linked dye-collagen substrate. Enzymatic activity is monitored by estimating the production of soluble dye-labeled collagen fragments resulting from the action of sample fluid proteases on the test substrate. Gingival fluid samples were collected on three successive days from 366 interdental sites in 34 volunteers, with and without periodontal disease. Results demonstrate that the assay is reproducible with 98.6% of sampled sites remaining stable throughout the 3-day study. Furthermore, the highest percentage of elevated neutral protease activity (NPA) values and the highest NPA values were found in patients clinically diagnosed as having advanced periodontal disease.

Evaluation Studies as Topic↗
PubMed1985

Effect of metal conditioners on porcelain-alloy bond strength.

The effect of three metal conditioners on the apparent bond strength of a single porcelain to four alloys was evaluated. On the basis of the bond strength data the following conclusions can be drawn. The use of metal conditioners provided no improvement in the apparent porcelain-alloy bond strength of Biocast and Biobond alloy. The use of Unibond alloy with its recommended conditioner Uniseal gave lower bond strength values than Unibond without the conditioner. With Rexillium III alloy the use of Uniseal gave the highest bond strength values, but these were statistically equal to those obtained with the recommended coating agent (Jeneric bonding agent). With the exception of Rexillium III alloy, it appears that coating agents may have a function other than bond strength improvement. In light of the continued marketing of new alloys, bonding agents, and porcelains, further research is needed to determine the mechanism of action of bonding agents as well as the porcelain-bonding agent-alloy interaction of various commercial products. Studies designed to address these topics are in progress.

Dental Alloys↗