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Biomedical subjects

J E Delaney

Publications and source records attributed to J E Delaney.

7 recordsLinked to original sources

Pediatric oral pathology. Soft tissue and periodontal conditions.

Pediatric patients can present with various intraoral lesions that require accurate diagnosis, treatment or reassurance, and possible referral for a dental evaluation. Periodic review of oral soft-tissue pathology can help the medical team to easily recognize common and rare abnormalities affecting children. Recent years have brought new insights into the causes and treatment of periodontal diseases of children, making prevention or treatment of many formerly untreatable conditions possible. Early detection of these oral conditions may be life saving.

Child↗

Periodontal and soft-tissue abnormalities.

Young children come to our offices with a variety of periodontal and soft-tissue abnormalities, which require accurate diagnosis, treatment or reassurance, and possible referral to our medical colleagues. Periodic review of soft-tissue lesions can help the dental team to recognize both common and rare abnormalities affecting young children. Recent years have brought new insights into the etiology and treatment of periodontal diseases of children, making it possible to prevent or treat many formerly untreatable conditions.

Child, Preschool↗

Microbiology of subgingival plaque from children with localized prepubertal periodontitis.

Localized prepubertal periodontitis has been described as a host-defect mediated form of bacterially induced periodontitis, with an early onset and rapid progression around a few teeth in children prior to puberty. To further our understanding of the etiology of this disease, we have examined the microbiological components of subgingival dental plaque in 9 children with localized prepubertal periodontitis to determine if patterns of putative pathogens existed, and have compared these results with those obtained from 4 children with no periodontitis. Subgingival plaque samples were plated onto a selective medium for Actinobacillus actinomycetemcomitans and onto a non-selective medium for anaerobes, and the predominant cultivable microbiota of 2 sites per child was determined. The subgingival microbiota of children with localized prepubertal periodontitis clearly differs from non-diseased children in the detection of high levels of several suspected pathogens, including A. actinomycetemcomitans, Bacteroides intermedius, Eikenella corrodens, and Capnocytophaga sputigena. These putative pathogens were found in various combinations. These findings suggest that localized prepubertal periodontitis is associated with specific subgingival bacteria which are generally not found in children without periodontitis.

Aggregatibacter actinomycetemcomitans↗