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Biomedical subjects

J E Fenn

Publications and source records attributed to J E Fenn.

10 recordsLinked to original sources
PubMed1979

Surgical principles and polytetrafluoroethylene.

This report describes a 24-month follow-up in 100 consecutive polytetrafluoroethylene (PTFE) arterial grafts. Although initial results were superb, a continued follow-up has showed extremely high closure rates for femoropopliteal and femorotibial grafts. The primary reason for this high attrition rate is thought to be stasis. We believe that PTFE is clearly the best synthetic arterial replacement available, but the material does not approach the autogenous saphenous vein in terms of long-term patency. Therefore, in spite of its many advantages, we do not recommend the elective use of PTFE for peripheral small-vessel bypass.

Bioprosthesis↗
PubMed1977

Reconstructive arterial surgery for ischemic lower extremities.

Patients with ischemic lower extremities who are to indergo arterial reconstruction must be carefully selected. A careful history and physical examination will disclose the point of obstruction and the degree of ischemia. Arteriography is essential for the determination of runoff adequancy below the point of obstruction and for selection of the best site for distal anastomosis. Various potential routes for bypass graft have been discussed and some of the factors that determine the procedure ultimately chosen have been presented. Types of graft materials currently enjoying popularity have been listed and the general techniques of operation have been outlined.

Aorta, Abdominal↗
PubMedDate not supplied

A successful transplant of embryonic adrenal tissue in a patient with Addison's disease.

Well documented reports of the successful transplantation of human adrenal cortical tissue cannot be found in the literature. In 1951 we achieved the successful transplantation of human embryonic adrenal gland (cortical tissue) in a patient with symptomatic adrenal insufficiency (Addison's disease), apparently the first instance of histologically documented successful homografting of human adrenal cortex. Because of its historical pertinence, the authors, many years later, herein report on this case, which appeared in the senior author's medical thesis. The report must be viewed in the context of the existing clinical knowledge and technology available 40 years ago.

Addison Disease↗