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Biomedical subjects

J E George

Publications and source records attributed to J E George.

At least 19 recordsLinked to original sources

Efficacy of cyhalothrin and lambdacyhalothrin against Boophilus microplus (Acari: Ixodidae).

A study was conducted to determine the efficacy of cyhalothrin and lambdacyhalothrin as a whole-body spray and lambdacyhalothrin as a pour-on application on cattle infested with Boophilus microplus (Canestrini). A laboratory bioassay was also done with both spray formulations. Cattle were infested with all parasitic life stages of B. microplus, then treated with 0.007 or 0.01% (AI) concentrations of cyhalothrin as a spray; 0.005, 0.007, or 0.01% (AI) concentrations of lambdacyhalothrin as a spray, or 1% (AI) lambdacyhalothrin as a pour-on. As determined by calculations of the index of reproduction (IR), the 0.007 and 0.01% (AI) cyhalothrin provided 92.4 and 97.3% control, respectively; the 0.005, 0.007, and 0.01% (AI) lambdacyhalothrin provided 92.4, 98.2 (average of two treatments) and 99.3% control, respectively; and the lambdacyhalothrin pour-on treatment provided < 50% control. Bioassay results indicated lambdacyhalothrin to be twice as effective as cyhalothrin against B. microplus.

Animals

AIDS.

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Acquired Immunodeficiency Syndrome

Legal issues in emergency radiology. Practical strategies to reduce risk.

Various joint commission and individual state standards affect emergency radiology practice and have legal implications. The ACEP has entered the burgeoning field of practice guidelines; fortunately, their practice guideline preparation system is arguably the most thorough in medicine at this time. This is of great importance to emergency physicians, because practice guidelines are not without their own potential legal, educational, and compliance problems. Trends toward cost-reduction through reduced radiograph utilization are a real phenomenon in all of medicine. It remains to be seen if costs can be reduced without increasing legal exposure. Excellent clinical guidelines are helpful to emergency physicians. The Massachusetts ACEP model, which appears to effectively blend closed claim data into practice guidelines, has built-in educational support and compliance incentives. This model may become a national standard in the future. Pediatric radiology risk management issues, such as the statute of limitations, have been discussed. Emergency physicians should be knowledgeable about the most commonly missed pediatric emergency radiologic diagnoses. Some aspects of common emergency radiology practice patterns are of relevance to a discussion of risk management in emergency radiology. Issues such as emergency physician radiograph interpretation responsibilities and follow-up systems emerge repeatedly in malpractice claims. The use of CQI strategies may prove helpful in improving practice patterns. Communication between emergency physician and radiologists is critical. Good communication requires the development of good rapport and should pay dividends in improved patient care.

Adult

Non-random mating between Boophilus microplus and hybrids of B. microplus females and B. annulatus males, and its possible effect on sterile male hybrid control releases.

When Boophilus microplus and Type-II hybrids (B. microplus females X B. annulatus males) were released simultaneously onto bovine hosts, mating between the two forms appeared not to be at random. There were more contypic and fewer intertypic matings than predicted under an assumption of panmixia. An examination of the patterns of matings revealed that more of the matings on the first two days of detachment were between the two sexes of B. microplus. Engorged females dropping on the last four days of maximum female detachment were predominantly hybrids mated to both B. microplus and hybrid males. The non-random mating pattern does not appear to be caused by assortative mating between B. microplus and Type-II hybrids, but because the B. microplus were competent to mate two days before the hybrids and the B. microplus males compete for males of both types better than the Type-II males.

Animals

Differential effects of photoperiod on development and reproduction in "montane" and "prairie" strains of the Rocky Mountain wood tick (Acari: Ixodidae).

Progeny of Dermacentor andersoni Stiles adults collected from one "montane" and two "prairie" sites in southern Alberta, Canada, were exposed to combinations of 9:15, 11:13 and 13:11 (L:D) daily photoperiods during various stages of their life cycle. Time required for developmental and reproductive events was recorded. Significant differences in mean molting times of fed larvae were observed, yet the differences were small, and mean times were not attributed to photoperiodic regime. Fed nymphal "prairie" ticks had significantly longer developmental rates under decreasing light regimes than in constant or increasing regimes, while "montane" ticks showed no differential response to any of these regimes. Engorged "montane" females in all regimes weighed significantly more than those in either "prairie" strain, and "prairie" strain females in increasing and constant short-day regimes were significantly heavier than those in decreasing and constant long-day regimes. Photoperiod is unimportant in the regulation of fed-larval development, and the magnitude of female engorgement may be nominally favored by short-day and increasing regimes. The differential phenotypic expression of photoperiodic regulation of fed nymphal development in this tick may have resulted from selective pressures involving differences in host availability and moisture conditions in the two geographic regions.

Alberta

Selective breeding for photoperiodically induced developmental diapause in laboratory strains of Amblyomma americanum (Acari: Ixodidae).

Offspring of Amblyomma americanum (L.) reared for four generations in a 12:12 (L:D) photoperiod in the laboratory were held in 10:14 (L:D) conditions and bred to select for developmental diapause (DIA) or nondiapause (NON) characteristics for two additional generations. Sequential generations of fed DIA nymphs had mean molting times (days from detachment to ecdysis) that were 8.0% (DIA1) and 35.7% (DIA2) greater than parental ticks, and maximal development time was extended by 20% in DIA2 ticks over that of parentals. Selection in NON strains resulted in a significant decrease of detachment to ecdysis times in NON1 ticks, but the detachment to ecdysis times in NON2 ticks increased and was not different from parental ticks. Breeding for DIA and NON extremes did not affect the ability of either strain to develop rapidly if held in long-light (14:10 [L:D]) conditions. Selection for DIA resulted in extension of the period from detachment of fed nymphs to preapolysial posturing rather than from posturing to ecdysis of adults.

Animals

Free-floating deep venous thrombosis. A retrospective analysis.

Duplex scan to diagnose deep venous thrombosis is an established technique. As experience accumulated, patients with free-floating thrombi were identified. A retrospective review of 65 patients was performed to study these thrombi, to evaluate treatment regimens, and to analyze patient outcome. A 26% incidence of pulmonary embolus occurred. However patients who had bilateral free-floating thrombi had a 42.8% incidence of pulmonary embolus. Receiving a 7-day course of heparin therapy with a partial thromboplastin time (PTT) at 1.5 times control was 53.2% of patients; 55.4% of the patients underwent follow-up examination, and the mean time to clot attachment was 9.2 days. Patients should receive anticoagulation for 10 days or until clot attachment. Patients with persistent, bilateral free-floating thrombi, or propagation of thrombus are candidates for potential caval interruption. Serial scans should be performed to monitor the thrombus for attachment or alteration.

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