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Biomedical subjects

J E Greivenkamp

Publications and source records attributed to J E Greivenkamp.

4 recordsLinked to original sources

Visual acuity modeling using optical raytracing of schematic eyes.

PURPOSE: We developed a methodology to predict changes in visual performance that result from changes in the optical properties of the eye. METHODS: Exact raytracing of schematic eyes was used to calculate the point spread function and the modulation transfer function of the visual system. The Stiles-Crawford effect, photopic response, diffraction, and the retinal contrast sensitivity are included in the model. Visual acuity was predicted by examining the modulation of the resultant retinal image of a bar target and by determining when the modulation falls below a threshold value. Visual acuity was predicted for refractive errors ranging from 0 to 5 diopters and for pupil diameters ranging from 0.5 to 8 mm. RESULTS: Visual acuity predictions were compared to clinically found Snellen visual acuities and were found to be highly correlated (r2 = .909). CONCLUSIONS: This modeling technique shows promise as a means of evaluating clinical and surgical procedures before undertaking clinical trails.

Contrast Sensitivity

Representation of videokeratoscopic height data with Zernike polynomials.

Videokeratoscopic data are generally displayed as a color-coded map of corneal refractive power, corneal curvature, or surface height. Although the merits of the refractive power and curvature methods have been extensively debated, the display of corneal surface height demands further investigation. A significant drawback to viewing corneal surface height is that the spherical and cylindrical components of the cornea obscure small variations in the surface. To overcome this drawback, a methodology for decomposing corneal height data into a unique set of Zernike polynomials is presented. Repeatedly removing the low-order Zernike terms reveals the hidden height variations. Examples of the decomposition-and-display technique are shown for cases of astigmatism, keratoconus, and radial keratotomy.

Cornea

Quantification of the Brückner test for strabismus.

PURPOSE: To measure quantitatively the change in the coaxial fundus reflex with varying degrees of ocular misalignment. METHODS: The coaxial fundus reflex was imaged with a charge coupled device camera under conditions of simulated ocular misalignment ranging from 0 degrees to 7 degrees of fixation eccentricity. The effects of refractive error and pupil size were controlled. Average gray scale brightness values were calculated for each bright pupil image after some image processing was performed on the raw images. RESULTS: A reliable, sharply delineated, minimum brightness at foveal fixation was observed. CONCLUSIONS: It is estimated that this technique can be automated to detect the presence of 2 degrees to 3 degrees of ocular misalignment based on the difference in brightness of the bright pupil images between the two eyes.

Adult

A low-cost computed tomographic scanner.

The authors describe a film-recorded computed tomographic (CT) scanner that uses optical processing methods for reconstruction of a sectional image. Results are comparable to commercial CT methods using the same patient dose. Consequently, clinically satisfactory CT imaging can be performed at a substantially reduced cost.

Animals