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Biomedical subjects

J E Jensen

Publications and source records attributed to J E Jensen.

At least 19 recordsLinked to original sources

An unusual ophthalmic tumour in a 5-year-old boy.

A rare tumour in a 5-year-old boy is presented and discussed. In time and location the story had two parts (Fig. 1): 1) a conjunctival granuloma at the nasal limbus of the right eye was surgically removed. 2) a few months later a huge lesion presented in the posterior segment of the same eye. Was it an ocular tumour with extension to the orbit or an orbital process with impression or invasion of the eye? Repeated surgical biopsies have indicated nodular scleritis of the posterior eye segment as the definitive diagnosis.

Child, Preschool

Changes in depressive-symptom experiences among older women.

Changes in depressive-symptom experiences over a 5-year period were investigated in a community sample of 251 women between the ages of 51 and 92 years. Findings from a confirmatory factor analysis of the SCL-90-R Depression and Additional Symptoms scales (Derogatis, 1983) indicate that two phenomenally different syndromes underlie symptom-reporting patterns. A depressive syndrome, more classic in form, shows decreasing levels with increasing age, although a depletion syndrome, marked by feelings of enervation and a loss of interest in things, shows increasing levels with advancing age. The relative independence of the two syndromes, as well as their differing relations to four more delimited forms of distress that were identified in the analyses, have important implications for future research on the age-depression relation.

Aged

Age differences in depressive symptom experiences.

Age differences in depressive symptom experiences were investigated in a community sample of 368 women between the ages of 51 and 92 who were administered the SCL-90 Depression and Additional Symptoms Scales. Confirmatory factor analysis was used to assess and compare depressive symptom experiences in a younger (age 51-65) and older (age 66-92) age cohort. Findings show that two somewhat different depressive syndromes underlie symptom reporting patterns, one having higher levels in the older age cohort, the other having higher levels in the younger age cohort. In addition, three more delimited forms of distress -- feelings of enervation, dysphoria, and sleep disturbances -- show higher levels among the older cohort. Implications of these findings for future research on the relation between aging and depression are discussed.

Aged

Revaccination against tetanus 17 to 20 years after primary vaccination: kinetics of antibody response.

In 24 military recruits vaccinated against tetanus 17-20 years earlier antibody responses were studied 4, 11, and 24 days after revaccination. Antitoxin concentration in serum showed a sigmoid increase with titres at day 4 only just above protective level, corresponding to a risk of susceptibility to be expected even 4 days after revaccination (2.0%, 95% confidence limit). Only after 7 days the risk of unprotection was less than 1%. As the incubation period of tetanus can be as short as 24 hours, revaccination only may not be regarded sufficient if more than 17-20 years have elapsed since primary vaccination and conditions favoring rapid development of tetanus are present. The findings may explain some of the cases of tetanus which have occurred in spite of primary vaccination supplemented by emergency booster. The statement that prophylactic tetanus immunoglobulin is never indicated to persons completely vaccinated earlier should be considered for revision.

Adult

"Ossifying" hemangiomas of the temporal bone: evaluation with CT.

Hemangiomas of the temporal bone that affect the facial nerve are more frequent than previously suspected. Six patients with slowly progressive or recurrent facial paralysis were evaluated with computed tomography. In each case, a lesion was demonstrated that enlarged the facial nerve canal and contained intratumoral spicules of bone. Typically the temporal bone was expanded by a lesion with an indistinct margin. Demonstration of the typical radiologic findings, especially the intratumoral bone spicules, makes hemangioma a much more likely diagnosis than schwannoma.

Adult

Systematic evaluation of acute knee injuries.

The high percentage of significant injury associated with a hemarthrosis correlates with the findings of Noyes, DeHaven, and others. The development of significant knee swelling immediately after injury should be an alarming sign. Our study revealed a significant probability of anterior cruciate ligament tear or meniscal tear in the acute hemarthrosis. Arthroscopy in acute hemarthrosis certainly should be considered and, in many cases, performed. Although not within the scope of this article, acute arthroscopic repair of a torn meniscus, evaluation of the degree of tear of the anterior cruciate ligament, and arthroscopic repair of osteochondral fractures are all benefited by acute arthroscopic examination. Decisions in diagnosis are helped by the knee aspiration.

Acute Disease

Library expansion.

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Libraries, Medical