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Biomedical subjects

J E Jones

Publications and source records attributed to J E Jones.

6 recordsLinked to original sources

Diagnostic evaluation of syphilis during pregnancy.

Obstetric patients with serologic evidence of syphilis should have cerebrospinal fluid (CSF) analysis to determine the presence of tertiary disease. In the present study, 19% of untreated and asymptomatic patients with serologic evidence of syphilis were found to have tertiary syphilis following examination of CSF. Despite maternal therapy, 11% of the infants born to mothers with syphilis had reactive serum and CSF involvement as documented by the presence of a fluorescent treponemal antibody absorption (FTA-ABS)-specific IgM.

Adult

Cephalexin monohydrate suspension. Treatment of otitis media.

Cephalexin monohydrate suspension was used in the treatment of 97 children with otitis media. Pretreatment middle-ear exudate specimens in pure or mixed culture yielded Diplococcus pneumoniae in 47 cases, Haemophilus influenzae in 26, Neisseria catarrhalis in 20, group A beta-hemolytic streptococci in 13, and Staphylococcus aureus in one. The usual dosage was 100 mg/kg/day given orally in divided doses for 10 to 12 days. After 48 hours of treatment, follow-up cultures showed that therapy had been successful in 90 children; 81 remained clinically and bacteriologically free of disease for at least three weeks following therapy. Of the seven children for whom therapy failed, H influenzae persisted in five and D pneumoniae in two. Acceptance of the drug was entirely satisfactory with no important side effects encountered.

Adolescent

Blood parameters in Leucocytozoon smithi infected poults fed clopidol.

Poults naturally infected with L. smithi demonstrated a significant (P less than 0.01) decrease in arterial PO2 (mm. Hg) during the second and third weeks after exposure to black fly bites. Poults fed Clopidol (0.0125%) during the exposure period and subsequent experimental periods showed very little parasitemia and no significant reduction in arterial PO2.

Animals

Changes in plasma electrolytes, acid-base balance and other physiological parameters of adult female turkeys under conditions of acute hyperthermia.

The effects of acute hyperthermia on certain physiological parameters of turkey hens was studied. It was found that the response of the turkey to hyperthermia is similar to the reported response of the chicken. The birds began panting and the average body temperature increased 0.1 degrees C. as the ambient temperature reached 32 degrees C. The panting or polypnea induced a profound respiratory alkalosis in the turkeys. The acute hyperthermia also caused a significant (P less than 0.05) decrease in plasma levels of sodium, total calcium, magnesium and inorganic phosphorus. The plasma level of potassium was significantly (P less than 0.05) increased.

Acid-Base Equilibrium

Acid-base balance, plasma electrolytes and production performance of adult turkey hens under conditions of increasing ambient temperature.

Turkey hens were exposed to stepwise increases in ambient temperature from 21 degrees C. to 25 degrees C. to 30 degrees C. to 35 degrees C. at two-week intervals. Dietary calcium levels to 1.54, 2.01 and 2.48 percent were fed. Acid-base balance, plasma electrolytes and production performance were studied. The temperature increase caused a significant (P less than 0.05) decrease in plasma sodium, calcium, and magnesium, and in egg production, shell thickness and egg weight and a significant (P less than 0.05) increase in plasma potassium. There was no significant change in the acid-base balance of the blood as measured by blood PO2, PCO2 and pH. Egg production was not significantly correlated to blood gas activitelated to plasma calcium and magnesium levels. Dietary calcium levels had no influence on the parameters measured.

Acid-Base Equilibrium