COMPARISON OF ACETARSOL AND PREDNISOLONE-21-PHOSPHATE SUPPOSITORIES IN THE TREATMENT OF IDIOPATHIC PROCTITIS.
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Biomedical subjects
Publications and source records attributed to J E LENNARD-JONES.
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These observations show that thiomersal, used as a bacteriostatic agent for retention enema solutions, irritates the colon. Investigations leading to the choice of a non-irritant bacteriostatic agent are described. The presence or concentration of sodium chloride in the solution does not seem to be important.
This paper presents the natural history of idiopathic proctitis and concludes that this disease and idiopathic procto-colitis are two manifestations of one disease differing only in the extent of the colon involved.
A double blind trial of prednisolone suppositories in out-patients with idiopathic proctitis is reported. Significant improvement was noted. When prednisolone suppositories were given after the patient had already used suppositories of base alone for three weeks the active treatment was no longer so effective.
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