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Biomedical subjects

J E Masters

Publications and source records attributed to J E Masters.

6 recordsLinked to original sources

Percutaneous Freehand system intramuscular electrode placement.

The FreeHand (NeuroControl Corporation, USA) system is an implantable electronic neuroprosthesis designed to stimulate muscles of tetraplegic upper limbs to achieve lateral pinch and simple grasp. When first introduced, the system required insertion through multiple large incisions, but recently introduced intramuscular electrodes have allowed the development of a percutaneous electrode placement technique. The technique minimizes incisions, decreases overall operative time and patient morbidity and improves the outcome by minimizing tendon adhesions.

Electric Stimulation Therapy↗

Randomised control trial of pH buffered lignocaine with adrenaline in outpatient operations.

Bicarbonate buffering of local anaesthetics is known to significantly decrease the pain of their administration and yet few practising surgeons do so. A double-blind randomised cross-over clinical trial was conducted to confirm the practicality and efficacy of bicarbonate buffering of lignocaine with adrenaline in the setting of a busy local anaesthetic operating theatre. 40 patients received either buffered or control local anaesthetic solutions in equivalent sites on opposite sides of the body. The pain of each injection was rated from 0 (no pain) to 10 (extreme pain). The mean pain score for the buffered solution was significantly lower than the control solution (3.06 vs 4.34, P = 0.002). Bicarbonate buffering of lignocaine with adrenaline is effective, inexpensive and simple; its widespread use should be encouraged.

Adrenergic Agonists↗

Comparative recovery from three nondepolarizing neuromuscular blockers in a patient before and after chronic anticonvulsant therapy: a case report.

We describe a 51-year-old patient undergoing a second neurosurgical procedure after being prescribed anticonvulsant therapy. The patient had significant changes in the duration of action of identical doses of nondepolarizing muscle relaxants and we were able to compare the duration of action of neuromuscular blockers before and after the chronic administration of anticonvulsant therapy. A brief review of the possible mechanisms of action of the acceleration of the patient's recovery profile is also presented.

Anticonvulsants↗