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Biomedical subjects

J E Nelson

Publications and source records attributed to J E Nelson.

61 records · Page 4Linked to original sources

Long-term outcome of learning and memory in children following severe closed head injury.

Seventeen children aged 5-16 years old (M = 11.3, SD = 2.97, Range= 6.25-16.00) were assessed between 4-5 years post-severe closed head injury, using the Wide Range Assessment of Memory and Learning (WRAML). Compared to age and sex matched controls, this group demonstrated deficits in the ability to learn new information, particularly their rate of learning. Deficits were more apparent with verbal than visual material. There were no indications of differences in delayed recall as measured by the amount of information lost nor in recognition memory. Results indicate that retrieval deficits may be an important component of memory difficulties in severe closed head injury. Educational implications are considered.

Adolescent↗

Assertiveness training using rehearsal and modeling with male alcoholics.

Two different forms of an assertiveness training program were designed for use in an inpatient ward at a VA hospital. Alcoholic subjects were pretested on self-report, behavioral and unobtrusive measures of assertiveness, and randomly assigned to one of three conditions: rehearsal group, modeling group, or discussion control group. Six 1-h group assertiveness training sessions were held over a 2-week period. On completion of the assertiveness training, trained subjects scored significantly higher on the measures of assertiveness than did controls; they also received more regular (vs irregular) discharges from the hospital. These alcoholic patients responded best to a treatment based on rehearsal. At a 2-month follow-up interview from date of discharge from the hospital, assertiveness trained subjects reported less drinking and more abstinent days than controls, though the differences were not statistically significant. Collateral report of subject behaviors generally agreed highly with subject report though collaterals gave slightly less favorable reports. Results were discussed in terms of the problems in conducting follow-up research and in terms of application to alcoholism treatment.

Adult↗

Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.

We examined the association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs) in a case control study of 417 prostate cancer patients and 420 group-matched control subjects. Regular daily use of over the counter NSAIDs, ibuprofen or aspirin, was associated with a 66% reduction in prostate cancer risk (odds ratio = 0.34, 95% confidence interval = 0.23-0.58, p<0.01). The risk of prostate cancer was also significantly reduced in men who reported taking prescription NSAIDs (odds ratio = 0.35, 95% confidence interval = 0.15-0.84, p<0.05). These results suggest that NSAIDs may have value in the chemoprevention of prostate cancer.

Anti-Inflammatory Agents, Non-Steroidal↗