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Biomedical subjects

J E Orme

Publications and source records attributed to J E Orme.

At least 19 recordsLinked to original sources
PubMed1983

Affective disorders and cognitive performance. A clinical report.

A study of 27 manic-depressives (some with histories of up to 65 years' duration and 100 attacks) showed that it is a disorder from which the patient can make a complete recovery without any cognitive deterioration. Many of these patients have had courses of the traditional drug and physical treatments (including ECT) used in mental hospitals over the last half century. This indicates that such treatments themselves need not produce deterioration.

Adult↗
PubMed1979

Amoxapine in depressive illness.

A double-blind trial was carried out in 29 patients recently admitted to hospital with depressive illness to compare the effectiveness and side-effect liability of treatment with amoxapine and imipramine. Both drugs were given in a dosage of 25 mg 3-times daily over a period of 4 weeks, and patients' progress was assessed using psychiatric and psychological rating scales for depression. Although amoxapine and imipramine proved equally effective, response to amoxapine was quicker and appeared to have the same effect after 1 week as did imipramine after 2 weeks. In addition, dryness of the mouth was complained of most frequently by patients taking imipramine.

Amoxapine↗
PubMed1975

Varieties of depression.

A factorial study was made of ratings on 51 depressed female patients of IMPS items related to depression. Four separate depressive factors that involved: (1) loss of motivation and energy; (2) feelings of depression and hopelessness; (3) feelings of guilt and sin; and (4) retarded behavior were obtained. Neither the patient's age nor the endogenous-neurotic distinction appeared to be important. A comparison of these results with other factorial studies of depression was made.

Adjustment Disorders↗