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J E Shelton

Publications and source records attributed to J E Shelton.

6 recordsLinked to original sources

Caloric requirements of a spastic immobile cerebral palsy patient: a case report.

This article documents the reduced caloric requirements for a spastic, immobile, cerebral palsy patient. We report an 11-year-old immobile, spastic, quadriparetic patient who remained obese despite receiving less than one half of the recommended basal caloric requirements for age. Basal metabolic rate was determined by indirect calorimetry using a Sensor Medics 2900 instrument. Standard reference sources indicate that an able-bodied 11-year-old child of comparable height requires 1,493 kcal/d for support of basal metabolic functions. Our patient was followed for 8 weeks on reduced calories and assessed for adequacy of diet by nitrogen balance studies and other appropriate parameters. Our data suggest that a subset of severely impaired children with cerebral palsy may require much less in total kilocalories per day for nutritional support than previous studies would indicate.

Age Factors↗

Patients' attitudes towards TIA.

Transient ischemic attacks (TIA) are an important forewarning of stroke. By means of questionnaire, information was sought from patients who suffered a stroke regarding whether or not they had a preceding transient ischemic attack. Those with a preceding transient ischemic attack were polled for their response to the TIA; 47% of patients with a transient ischemic attack did not seek medical attention. The reasons behind failure to seek medical advice are analyzed.

Adult↗

Functional scoliosis as a long-term complication of surgical ligation for patent ductus arteriosus in premature infants.

Follow-up evaluation was performed on two groups of children, all premature infants who had undergone surgical ligation of a patent ductus arteriosus in the first days of life (Group I, 12 months postligation; Group II, 4 years postligation). Overall, two of 11 patients had significant functional scoliosis associated with weakness of shoulder girdle musculature and three additional patients had functional weakness on the affected side but with normal vertebral alignment. Patients post-patent ductus ligation should be observed for this long-term complication.

Ductus Arteriosus, Patent↗

Somatomedin activity before and after chelation therapy in lead-intoxicated children.

Somatomedin activity was measured in 21 lead-intoxicated children to determine whether plumbism interferes with the processes of statural (bone) growth. Somatomedin activity was measured both by the rabbit coastal cartilage bioassay and by radioimmunoassay of somatomedin-C. Compared to values in normal children, both the bioassay and radioimmunoassay somatomedin activity was increased. The degree of body lead burden was so extensive that the 21 study children required chelation therapy. Following EDTA or BAL + EDTA chelation therapy, the overall somatomedin activity of these children with plumbism further increased significantly. In contrast, measures of body lead burden--including blood lead levels--decreased after treatment in all lead-intoxicated youngsters. We conclude that plumbism is associated with increased somatomedin activity. Hence the increased somatomedin activity may explain why clinical experience fails to find any long-term deleterious effect of saturnism on statural (bone) growth. Possible mechanisms underlying the increased somatomedin activity in the lead-intoxicated children remain to be defined.

Calcium↗