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J E Waters

Publications and source records attributed to J E Waters.

7 recordsLinked to original sources
PubMed2002

The structure and function of catalytic domains within inositol polyphosphate 5-phosphatases.

Phosphoinositide signaling pathways regulate many essential cellular functions including proliferation, differentiation and survival, cytoskeletal organization, and vesicular trafficking. The inositol polyphosphate 5-phosphatases regulate the cellular levels of several bioactive phosphoinositide species. This review describes the structure and function of the 5-phosphatase and Sac1 catalytic domains of these enzymes. The crystal structure of the 5-phosphatase domain has been solved and shares homology with members of the AP endonuclease family. The phosphoinositide polyphosphatase activity of the Sac1 domain, found in some inositol polyphosphate 5-phosphatases, is defined by a motif, CX5 R(T/S), also found in both protein and lipid phosphatases.

Amino Acid Sequence↗
PubMed1991

Dysfunctional family systems: relationships to disordered eating behaviors among university women.

Clinicians have speculated that the appearance and maintainance of eating-disordered behavior may be attributed to certain familial characteristics which predispose vulnerable individuals to the development of these behaviors. However, few empirical studies exist to substantiate these speculations. This study compared the responses of 190 female university students on three self-report instruments: the Disordered Eating and Weight Control Instrument (DEWCI), the Eating Disorders Instrument (EDI), and the Family Adaptability and Cohesion Evaluation Scale (FACES III) to identify potential relationships between eating-disordered behavior and family types. Subjects were classified, on the basis of their scores on the FACES III, into one of three family types: balanced, midrange, or extreme. A one-way analysis of variance with main effect for family type was applied to the eating-behavior subscales. A Turkey multiple comparison test was applied to the significant main effects. Women classified in the extreme family type scored significantly higher (p less than .05) on several measures of eating-disordered behavior. A Distance From Center (DFC) linear score also was computed and correlated with the eating-disordered subscales. All but 4 of the 18 measures correlated significantly (p less than .05). These findings support speculation, particularly that of family theorists, that eating-disordered behavior may be a symptom response and/or coping strategy for women in dysfunctional families.

Adaptation, Psychological↗
PubMed1980

Social ecology: a method for evaluating groups.

The applicability of social ecology as a means to evaluate psychotherapy groups is discussed by means of a case example. A Couples' Growth in a community alcohol treatment programme was used to demonstrate a social ecological approach to the assessment and description of groups. Members' and leaders' perceptions of the group's social environment, as well as perceptions of an ideal group, were determined via a recently developed Group Environment Scale. This assessment pointed to areas of discrepancies, and the results were validated in a "group feedback session". Systematic data on the social ecology of groups will enable clinicians to better evaluate and describe this treatment setting in which behaviour change is being attempted.

Adult↗