Biomedical subjects

J E Whitley

Publications and source records attributed to J E Whitley.

4 recordsLinked to original sources

PubMed1989

Iron for the suckling.

Knowledge of the metabolism of iron by young infants is incomplete but combining practical studies based on detecting the onset of iron depletion with isotopic studies of iron economy may improve our understanding of iron metabolism in infants and our strategies for ensuring their iron supply. The iron accumulated by the fetus is enough to delay the risk of iron deficiency until four, and two months of age in term and preterm infants respectively. Breast fed term infants may not need extra iron until they are six months or older; but whereas low iron formulas are adequate for other infants until about four months of age, thereafter infants need extra iron which can be provided effectively in iron fortified formulas. Breast fed low birth weight infants need iron supplements from two months of age but those fed specific low birth weight formulas which are iron fortified should not need extra iron.

Food, Fortified↗

PubMed1988

Uptake and excretion of inorganic mercury in the lobster Homarus gammarus (L.) White 1847: long-term effects of exposure to low levels of the metal.

The uptake and accumulation of inorganic mercury by lobsters, from seawater containing levels of 10 to 100 ppb, was studied over periods of up to 50 days, using radiochemical neutron activation analysis. These results were amplified by the use of radioisotope tracer experiments. It was found that the gills and the green glands accumulated the most mercury and that the metal could be excreted via the urine. Histological studies showed that long-term exposure to mercury resulted in progressive necrosis of the green glands, whereas other organs were unaffected.

Animals↗

PubMed1987

Abdominal CT in the staging of small-cell carcinoma of the lung: incidence of metastases and effect on prognosis.

CT studies of the abdomen performed on 72 patients with small-cell carcinoma of the lung were retrospectively reviewed to assess the role of abdominal CT in staging. Forty-four of the 72 patients had extensive disease, defined as disease extending beyond the confines of one hemithorax, plus or minus mediastinal or ipsilateral supraclavicular disease or ipsilateral pleural effusion. Initial-staging abdominal CT revealed one or more sites of metastatic disease in 26 (59%) of these 44 patients, while 18 patients had normal initial CT examinations. Statistical analysis of patients with extensive disease revealed a significant increase in complete therapeutic response (p = .0054) and in the length of survival (p = .001) among those who had extensive disease without abdominal metastases as compared with those who had abdominal metastases on their initial abdominal CT examination. The development of new or recurrent abdominal metastases in general or in specific organs on follow-up scans obtained in 35 patients did not significantly decrease their survival time as compared with that of patients without such metastases. Our findings suggest that CT of the abdomen is beneficial in the initial staging of patients with small-cell carcinoma of the lung and provides prognostic information concerning response to therapy and length of survival.

Abdominal Neoplasms↗

PubMedDate not supplied

Teaching and learning.

Explore the source record for details and available documents.

Education, Medical↗