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Biomedical subjects

J E Wickham

Publications and source records attributed to J E Wickham.

148 records · Page 9Linked to original sources

Hydrophilic graft copolymers: a new concept in urological surgery.

Hydrophilic graft copolymers are derived from hydrophobic polymers which have been copolymerized and then grafted by radiation initiation so that they become hydrophilic. Tubes of such material expand in diameter by 60% when wet and become slippery. The first medical applications of these materials are described: they have been used as an access conduit for percutaneous renal surgery and endoscopic access to the ureter.

Acrylates↗

The development and application of a new surgical device--the Endoscopic Liquidiser and Surgical Aspirator (ELSA).

Modern surgery is looking for ways to carry out procedures which limit unnecessary damage to the patient. This means, in practice, using smaller incisions and special tools. An instrument for removing tissue through a small cross-section has been developed. It is suitable for both endoscopy and laparoscopy. The instrument and its development is described, and its performance evaluated in vitro and for a range of clinical procedures. Experiments aimed at uncovering the mechanism of cutting are discussed as to their relevance for practical instrument development.

Aged↗

The management of urinary calculi in a stone centre.

We report the management of the first 100 patients who presented with upper urinary tract calculi to The Devonshire Hospital Lithotripter Centre. Ninety-two patients were treated by extra-corporeal shock-wave lithotripsy (ESWL) alone, four by percutaneous nephrolithotripsy (PCN) and two with staghorn calculi by combined ESWL and PCN. Ten patients had ureteric stones, and two of these required conventional open surgery. The average inpatient stay was 3.7 days. Half the patients required no analgesia after ESWL. Of the remainder, most were comfortable with oral analgesia. Almost all returned to normal activity within a few days of discharge. Complications were minimal and were managed by percutaneous or endoscopic techniques. These figures confirm the West German experience that ESWL is a safe and effective urological procedure and requires a skilled back-up of percutaneous and ureteroscopic skills for optimal patient management. By means of these techniques, conventional open surgery is necessary for the treatment of fewer than 5% of cases of calculi in the upper urinary tract.

Adolescent↗