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Biomedical subjects

J E van Bronswijk

Publications and source records attributed to J E van Bronswijk.

At least 19 recordsLinked to original sources
PubMed1998

Quantifying the potential for independent living in COPD-patients.

In patients with Chronic Obstructive Pulmonary Disease (COPD), daily physical functioning as quantified by energy expenditure, is limited by decreased ventilatory capacity and increased basal metabolic rate in relation to their physical capacity. Starting from the Dutch Health-Care situation, a measurement interpretation model is presented to quantify individual potential for independent living from energy expenditure, aerobic capacity and lung function. The interpretation model concerns only simple routine measurements. After further validation, this model will be used in predicting the clinical effects of environmental improvements.

Activities of Daily Living↗
PubMed1993

Clinical improvement after unusual avoidance measures in the home of an atopic dermatitis patient.

A 27-year-old female office clerk with widespread atopic dermatitis (AD) since infancy appeared to be highly sensitized and exposed to molds, storage mites, and chicken feathers and moderately sensitized to house-dust mites and grass and birch pollens. Hardly any textiles were present in her home; that is, only 28 m2, which is less than 25% of the Dutch national average. The causal relationship between eczema and molds plus storage mites in this case of AD was strengthened by the positive effect of an unusual, multidisciplinary home-sanitation program involving cleaning of mineral surfaces and ventilation improvement. This home-sanitation program led to a gradual drop of total IgE and clinical symptom scores to 21% and 13%, respectively, of the original values.

Adult↗
PubMed1992

Mechanisms and patient compliance of dust-mite avoidance regimens in dwellings of mite-allergic rhinitic patients.

We report on the mechanisms, the environmental changes and patient compliance with regard to conventional and new dust and mite avoidance measures to prevent allergic symptoms caused by mite allergens, taking into account both allergen contamination and the developmental success of pyroglyphid Acari. Twenty patients with persisting rhinitic complaints were selected and matched. Although the patients had performed some conventional dust and mite avoidance measures (patient compliance was 90%), the dwellings proved to be a stimulus for mite development. Moisture problems due to faulty construction and excessive moisture production were common. Since humidity conditions could not be changed at short notice, the 20 homes were subjected to the new variants of mite allergen avoidance based on intensive cleaning without (control) and with an acaricide incorporated (acaricidal cleaner [Acarosan]). After the carrying out of conventional avoidance measures, these patients still had allergic symptoms, and dust from only 23 to 52% of their textile objects was under the proposed guanine (mite faeces indicator) risk level. Only the acaricidal cleaner was able to decrease the allergenic mite load (and the burden of the patients) significantly in this 12 month period. With respect to mite-extermination, acaricidal cleaning was 88% better than intensive cleaning. Reduction of guanine was 38% better in the Acarosan treatment group. Clinical results have been reported elsewhere. A significant difference in favour of the acaricidal cleaning was seen in both subjective (as regards symptoms) and in objective data (total IgE). Another 50 patients were questioned.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1986

Guanine as a hygienic index for allergologically relevant mite infestations in mattress dust.

Since guanine is not only an essential constituent of vital nucleic acids, but also the main end product of nitrogenous waste excretion in arachnids, it is a potential candidate for a hygienic index for mite activity in house dust. The public health significance of these mites is based on their production of allergen in the home environment. In 101 mattress-dust samples, total number of mites and guanine content were positively correlated. The hygienic standard of 10 mites per 0.1 g dust (as derived from Danish investigations) was met in all samples with less than 0.06% guanine in the dry dust. Where the guanine content was more than or equal to 0.25% in the dry dust, mite numbers were higher than 10 mites per 0.1 g dust in 43 of the 44 samples. The three different groups (negligible mite content, possibly allergologically relevant mite concentration and allergologically unhygienic mite situation) could be easily discriminated on the color scale. The guanine-AZO-dye reaction in vacuum cleaner dust is a strong and promising candidate for an allergologically relevant hygienic index in the home.

Allergens↗
PubMed1980

A bibliography on ticks and tick-borne diseases in the countries of the Benelux (1567-1978).

Information published between 1567 and 1978 on this subject contains at least 223 titles. They cover medical and veterinary as well as biological aspects. Full bibliographical details of the publication are given. A subject index (to tick species, host species, and diseases transmitted) increases the availability of the data included. Some of the more interesting results of the study are discussed in a short introduction.

Animals↗
PubMed1980

[The brown dog tick Rhipicephalus sanguineus Latreille 1806 in the Netherlands, an analysis of imported cases, including their veterinary and medical significance (author's transl)].

Eighteen cases of infestation with Rhipicephalus sanguineus were reported during the past five years. Of the cases, six were observed during the first seven months of 1979. Of all infestations, four originated from sources within the territory of the Netherlands. Several cases of infestation with canine babesiosis were reported. There could have been a relationship between some of these cases and infestation with R. sanguineus. Populations of this tick can survive and develop in Dutch homes. Forming reservoirs of boutonneuse fever and canine babesiosis would appear to be possible.

Animals↗
PubMed1978

An evaluation of biological methods in house-dust allergen research.

Methods in house dust analysis pertaining to particle identification, to extraction and identification of mites, other arthropods, fungi, bacteria and algae are evaluated. As far as possible, quantitative data are given to compare the extractive efficiency of the different methods.

Allergens↗
PubMed1977

[Mange caused by Trixacarus in guinea-pigs (authors transl)].

Six cases of mange in guinea-pigs due to the mite Trixacarus caviae (F ain et al., 1972) are reported. The clinical and histological features are described. In spite of the alarming symptoms occasionally shown by guinea-pigs, the usual antiparasitic therapy was effective. Morphological features by which T. caviae may be differentiated from Sarcoptes scabiei and Notoedres muris, are reviewed.

Animals↗