PubMed HealthSearch

Biomedical subjects

J Edeiken

Publications and source records attributed to J Edeiken.

17 recordsLinked to original sources

Chondrosarcoma: MR imaging with pathologic correlation.

Magnetic resonance (MR) images of 21 surgically confirmed chondrosarcomas were retrospectively reviewed in conjunction with plain radiographs and computed tomographic scans and correlated with pathologic findings. The tumors appeared lobulated, and signal intensity, as analyzed visually (intermediate on T1-weighted, high on T2-weighted images), was similar for all lesions, regardless of pathologic type. Size of lesion was not an indicator of grade. The appearances of mesenchymal and dedifferentiated chondrosarcomas mimicked that of conventional chondrosarcoma. Extraskeletal chondrosarcoma was visualized as a lobulated soft-tissue mass. In all cases, MR imaging accurately depicted intraosseous and soft-tissue extent of tumor noted at surgery and pathologic examination. Histologic type or grade of chondrosarcoma generally cannot be characterized on the basis of visual analysis of signal intensity noted on routine MR images. However, MR imaging is excellent for exact delineation of tumor extent.

Bone Neoplasms

Imaging of the normal spine, developmental anomalies, and trauma of the spine and extremities.

Many significant papers in the current literature have considered the spectrum of developmental and traumatic alterations in the spine. The increasing role of MR and CT imaging is stressed as well as the continued importance of conventional radiography. The distinguishing features and pathology of developmental anomalies and traumatic injuries and the importance of accurate and complete diagnosis are discussed. This review includes articles that emphasize imaging of the normal spine, congenital anomalies, and trauma of the spine and extremities.

Extremities

Easily missed trauma of bones and ligaments.

While most fractures and dislocations are easily detected by radiographic and physical examination, some traumatic events are overlooked because the normal radiographic anatomy is not appreciated. Furthermore, certain routine radiographic views are inadequate to detect specific injuries. "Chip" or "sprain" fractures are often considered minor injuries when they actually connote significant injury to ligaments and capsules. These injuries are usually dismissed by the primary care physician, who does not believe them serious enough to warrant consulting an orthopedic surgeon. However, some are also overlooked by radiologists and orthopedic surgeons. If these injuries are not treated adequately, permanent loss of function or death may result. With these thoughts in mind, we will describe some of these injuries and discuss the radiographic anatomy, the knowledge of which should preclude some of the serious mistakes of diagnosis.

Bone and Bones

Parosteal osteogenic sarcoma arising in cranial bones: clinical and radiologic features in eight patients.

Parosteal osteogenic sarcoma is a distinct surface bone tumor with a better prognosis than conventional osteogenic sarcoma. We studied eight histologically proved cases of cranial parosteal osteogenic sarcoma. The tumors were identical in histologic appearance to parosteal osteosarcoma arising in long bones. Clinically, the tumor presented as a hard, painless, nodular scalp mass. The prevalence in women outnumbered that in men by 3:1, with most cases occurring between the second and third decades of life. Plain radiographs showed a rounded, sessile bone growth of variable size arising from the outer table of the skull. The tumor was heavily ossified centrally with variable margins and, at times, with radiating bony spicules at the periphery. No satellite bone nodules were noted in adjacent soft tissues. In three cases a fine radiolucent cleft was demonstrated between the tumor and the underlying outer table on the tangential radiographs or CT. After en bloc resection of the tumor, follow-ups for 20 years in one patient and 1 year in two patients showed no recurrence. Parosteal osteosarcoma of the skull is a rare low-grade tumor that usually arises from the outer table of the skull and has distinctive radiologic features that should distinguish it from other exophytic cranial bone neoplasms.

Adolescent

Radiologic concepts of lymphoma of bone.

The imaging of lymphoma of bone is illustrated by conventional radiology, computed tomography, magnetic resonance imaging, and nuclear radiology. The features of non-Hodgkin's lymphoma are demonstrated.

Bone Neoplasms

Prognostic factors of breast neoplasms detected on screening by mammography and physical examination.

A total of 183 neoplasms detected on screening women between the ages of 45 and 64 by mammography and physical examination were analyzed according to multiple histologic parameters. In general, tumors apparent only on mammography should be associcated with favorable long-term survival because of their early stage. These lesions had histologic features indicating significant potential for subsequent metastatic spread. This analysis strongly suggests that mammographic screening of asymptomatic women both above and below 50 years of age can substantially reduce breast cancer mortality.

Breast Neoplasms

Ankle trauma.

Explore the source record for details and available documents.

Ankle Injuries

Tubular carcinoma of the breast. Mammographic appearance and pathological correlation.

Xeromammographic and pathological findings in 17 cases of tubular carcinoma of the breast are presented. No patients had axillary lymph node involvement. The mean lesion size was 0.95 cm. Thirteen lesions (76%) were clinically occult. Because of the characteristic histological pattern of infiltrative growth and marked desmoplasia, 81% (13/16) were seen on xeromammography as scirrhous masses, 19% (3/16) only as microcalcifications. None appeared as a well-circumscribed mass or poorly defined density.

Aged

Thermography, mammography, and clinical examination in breast cancer screening. Review of 16,000 studies.

Breast cancer screening detected 139 biopsy-proved malignancies in 16,000 slef-selected women (8.7/1,000). In these, xeroradiography detected 78% (109), clinical examination 55% (76), and thermography 39% (54). In all 16,000 women, the thermogram was interpreted as positive in 17.9% (2,864). The greatest effectiveness of mammography vs. clinical examination was seen in detection of early breast cancers (small lesions with negative axillary lymph nodes). In this group, thermography was less effective than it was in patients with larger lesions and lymph node metastases.

Breast Neoplasms

Analysis of clinically occult and mammographically occult breast tumors.

Findings by xeromammography and clinical examination were compared in 16,000 self-selected women aged 45-64 who participated in a voluntary breast cancer screening program. A total of 138 malignancies were detected: 108 (78%) by mammography and 78 (57%) by clinical examination. Mammography was more effective for large breasts, fatty breasts, and in older women. Conversely, clinical examination was more effective for small breasts, dense breasts, and retroareolar lesions. Clinical detection decreased strikingly for lesions with negative lymph nodes, in situ and microinvasive lesions, deeply situated lesions, and lesions where microcalcifications were the sole mammographic finding.

Age Factors

Vertical fissure line in a normal adult.

The major fissure when directed in the sagittal plane is visualized on a frontal roentgenogram. It is reported in infants and children as the vertical fissure line and may occur with cardiomegaly and/or respiratory infection which rotates or partially collapses the lower lobe. Its presence in a normal adult chest is presented. It is believed to represent a congenital positional variant.

Cardiomegaly

Juxtasellar hyperostosis of non-meningiomatous origin.

Seven patients are described who had juxtasellar hyperostosis with visual disturbance secondary to non-meningiomatous lesions. Two had chromophobe adenomas, one craniopharyngioma, one carcinoma of the sphenoid sinus, one a thrombosed aneurysm of the intracavernous portion of the internal carotid artery, one epidermoidoma of the orbit, and one chondroblastoma of the anterior clinoid process. The diagnosis of meningioma was entertained initially on the basis of hyperostosis plus visual impairment. Careful evaluation of hyperostosis is essential for correct diagnosis of meningioma, according to our experience. Suprasellar meningiomas almost invariably produce irregular hyperostosis of the planum sphenoidale, often associated with serration and blistering. Sphenoid meningioma, when it is sclerotic, always shows thickening or expansion of the sphenoid wings. Therefore, in the absence of typical meningiomatous hyperostosis, one can readily differentiate non-meningiomatous hyperostosis from true meningioma.

Adenocarcinoma