Biomedical subjects
Publications and source records attributed to J Eliasoph.
Incarcerated obturator hernia is an uncommon entity that on occasion may produce specific radiographic findings and clinical signs (Howship-Romberg sign) that permit diagnosis prior to celiotomy. A case is reported in which the diagnosis was suggested when pain in the thigh was elicited during the course of a barium enema examination.
One hundred randomly selected inpatients were examined with both double-contrast barium meal and endoscopy in a blinded prospective fashion. All studies were done by staff personnel, with equal clinical information available to both the radiologist and endoscopist. The final diagnosis was made by a review committee of participating radiologists and endoscopists. Endoscopy was more sensitive (92% versus 54%, p less than 0.001) and specific (100% versus 91%, p less than 0.05) than the double-contrast barium meal. Both procedures significantly affected the clinical outcome of the patient, the effect of endoscopy being significantly greater than that of the double-contrast barium meal. Although errors with the barium study related predominantly to an inability to show subtle lesions, poor patient cooperation and perceptual and technical failures were additional significant factors. Endoscopy is recommended for certain groups of patients.
Crohn's disease involving the duodenum is rare and is usually associated with Crohn's disease elsewhere in the alimentary tract. Seven patients were treated at the Los Angeles County-University of Southern California Medical Center with complications of Crohn's disease involving the duodenum. These included two patients with abscess and duodenoileocolocutaneous fistulas, two with gastrointestinal tract bleeding, one with gastric outlet obstruction, and two with symptoms of small-bowel disease only. Four of the seven were successfully treated nonoperatively with a variety of modalities, including ulcer regimen, sulfasolazine, adrenocortical steroids, enteric rest, and total parenteral nutrition. Three patients required surgery, one for intractable bleeding and two for enterocutaneous fistulas. The majority of patients with duodenal Crohn's disease can be treated nonoperatively, with resolution of symptoms and roentgenographic healing of lesions. Surgical intervention is only advocated for those patients with complications that do not resolve with nonoperative therapy.
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