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Biomedical subjects

J Endrys

Publications and source records attributed to J Endrys.

At least 37 records · Page 2Linked to original sources

Catheter for visualization of patent ductus arteriosus.

We have developed a new catheter for transvenous angiography in patent ductus arteriosus (PDA) that has given excellent results in 31 patients (age range seven months to 17 years). Optimal selective opacification of PDA is due to maintaining the catheter side holes in close proximity to the PDA and to rapid delivery of relatively large volumes of contrast medium into the ampulla of the PDA without the catheter recoiling. The venous route of catheter insertion precludes possible arterial injury.

Cardiac Catheterization↗

Decompression of the left ventricle in the recovery period during myocardial revascularization.

Effective left heart decompression is essential for the reduction of myocardial oxygen consumption during recovery from an induced ischemic insult. During the early postischemic recovery phase of patients undergoing aorto-coronary bypass surgery, left ventricular, left atrial and aortic pressures were measured in non-vented hearts and in 2 types of left ventricular decompression. The following findings were made: Total cardiopulmonary bypass with effective decompression of the left ventricle decreases peak systolic left ventricular pressure, thereby reducing oxygen consumption of the myocardium. In this way adequate conditions are provided for recovery of the myocardium after unclamping of the aorta. The best method for decompression appears to be the placing of a large-lumen cannula in the left ventricle and allowing the blood to pour freely from the vent. The zero or near zero left ventricular filling pressure achieved with total cardiopulmonary bypass but without ventricular decompression does not prevent the chamber from producing isometric pressure work with peak systolic pressure reaching 80 to 90 torr. The hazard of air embolism may be reduced by precautionary measures. Left atrial monitoring permits recognition of pressure decreases to negative values. Active suction of the blood from the left ventricle is dangerous and should be avoided.

Blood Pressure↗

Possibilities and limitations of non-invasive techniques for the study of left ventricular function in chronic pulmonary disease.

The authors examined systolic time intervals, apexcardiograms and left ventricular echocardiograms in 151 patients with chronic disease of the airways. Their study showed that unlike apexcardiograms and echocardiograms, which can be performed in 33.8% and 56.7% of patients respectively, systolic time intervals can be assessed in 90.1% of patients. Pathological values of left ventricular function parameters were a comparatively common finding: 49.2% in systolic time intervals, 35.1% in apexcardiograms and 23.5 % in echocardiograms. There was no relation between the parameters of pulmonary function and those of left ventricular function. The authors hold that non-invasive examination of the left ventricular function in pulmonary disease is most valuable in long-term follow-up studies of the changes of the above parameters.

Chronic Disease↗

Left ventricular overload caused by collateral pulmonary circulation in chronic pneumopathies-myth or reality?

The collateral pulmonary blood flow was measured by the dye dilution method in four patients with chronic obstructive pulmonary disease, in 16 patients with diffuse pulmonary fibrosis, in 15 patients with pulmonary embolism, and in three patients with primary pulmonary hypertension. The authors found that collateral pulmonary circulation was small in the first two groups (0.3 % and 1.7% of the pulmonary blood flow, respectively), absent in primary pulmonary hypertension, and high (14.0% of pulmonary flow) in pulmonary embolism. The magnitude of the bronchopulmonary collateral circulation did not correlate with degree of precapillary pulmonary hypertension, left atrial pressure and left ventricular enddiastolic pressure. It seems that the bronchopulmonary collateral flow does not produce diastolic left ventricular overload in chronic pneumopathies.

Chronic Disease↗

The limitation of mitral echocardiography in combined mitral lesions.

In combined mitral stenosis and incompetence, the mitral echocardiogram is able to estimate the degree of mitral stenosis (i. e. mitral valve area) without being able to detect or quantify mitral incompetence. A diastolic closure rate of 20 mm/sec or less does not exclude significant mitral incompetence as claimed by others. Cardiac catheterization is still necessary in mitral stenosis, where concominant mitral incompetence is suspected clinically, to confirm its presence and quantify its degree.

Cardiac Catheterization↗

The effect of atrial pacing on the mitral echocardiogram of mitral stenosis recorded simultaneously with haemodynamic data.

Simultaneous mitral echocardiograms and haemodynamic data were recorded in six cases of mitral stenosis during atrial pacing. Due to the prolongation of the P-R interval during atrial pacing, the diastolic closure rate E-F was measurable up to a heart rate of 80 per min. only. At a heart rate of 80 or less, both in sinus rhythm and during atrial pacing the diastolic closure rate remained essentially the same in each case. However, above 80/min E-F became too short and post-atrial systolic closure A-B only was available for measurement which was higher in each case than its corresponding E-F value. This contrasts with cases with sinus rhythm where the diastolic closure rate E-F measurable up to a heart rate of 110 per minute.

Cardiac Output↗