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Biomedical subjects

J F Ceccon

Publications and source records attributed to J F Ceccon.

At least 19 recordsLinked to original sources
PubMed1995

[The Institute of Tropical Ophthalmology of Africa].

The Tropical Ophthalmology Institute of Africa (TOIA) is an integral part of the OCCGE. Located in Bamako since 1953, the TOIA is operated jointly by the member states of the OCCGE, the French Cooperation Ministry, and the WHO for which it serves as a center for the prevention of blindness. In addition to providing eye care for the people of western Africa, the TOIA promotes clinical, epidemiologic, and surgical research and carries out health surveys in function of the needs of the member states of the OCCGE. The major purpose of the TOIA is to training doctors and ophthalmologic nurses as well as for cataract operators and eyeglasses technicians. At the center of a network dedicated to the fight against blindness, the range of action of the TOIA now reaches beyond the borders of the eight states in the OCCGE.

Academies and Institutes↗
PubMed1993

[Expulsive hemorrhage (report of 2 cases)].

Two cases of expulsive haemorrhage consecutive to an operation of intumescent cataract responsible of major ocular overpressure (60 and 70 mmHg) are reported by the authors. No other risk factor has been found in our patients, one of 45 years old and the other 72 years old. First nor the operative wound suture neither the posterior sclerotomy were stitched, because of the inability to discover the site of choroidal haematoma with quat amount of blood in the operative field. The second reason was the use of an inadequate material of suture (vicryl 9/0). Finally both cases presented were eyes without any light perception. The final phase results in phtysis phenomena.

Aged↗
PubMed1992

Efficacy of massive oral doses of retinyl palmitate and mango (Mangifera indica L.) consumption to correct an existing vitamin A deficiency in Senegalese children.

Administration of large oral doses of retinyl palmitate has become the most widely practised vitamin A deficiency prevention strategy in developing countries. We conducted a follow-up study among 220 Senegalese children aged 2-7 years suffering from moderate undernutrition to determine the efficacy of vitamin A treatment on their vitamin A status assessed by biochemical and cytological (impression cytology with transfer) methods. The first examination (T = 0 m[onth]) was carried out during April 1989, before the mango (Mangifera indica L,) harvest. The second examination (T = 2 m) was carried out 2 months after vitamin A treatment during June 1989 when ripe mangoes become widely available. Conjunctival cells of the eyes of the children with or without ocular inflammation were responsive to vitamin A administration (P < 0.01). There was a significant increase (P < 0.001) in mean serum retinol and beta-carotene levels between T = 0 m and T = 2 m. Mean serum retinol-binding protein (RBP) and transthyretin (TTR) levels did not differ significantly (P > 0.05) at T = 0 m and T = 2 m. Despite the intake of vitamin A, 54% of the children who had abnormal cytology at T = 0 m remained abnormal at T = 2 m. This was due to inadequate levels of TTR and RBP, presumably due to the cereal diet eaten by the Senegalese population. children with abnormal eye cytology had lower serum retinol levels than those with normal eyes at T = 0 m, and beta-carotene values did not correlate with eye cytological abnormalities at T = 0 m. Children with normal cytology had higher serum retinol and also beta-carotene levels than those with abnormal cytology after massive oral doses of vitamin A and consumption of mangoes at T = 2 m. Retinyl palmitate may, therefore, only lead to partial cytological improvement due to a lack of retinol-carrier proteins but dietary beta-carotene may also be involved.

Carotenoids↗
PubMed1992

Assessment of the vitamin A status of preschool and school age Senegalese children during a cross-sectional study.

The increasing concern about vitamin A deficiency in even its mild subclinical form has created the need for a mass screening test. Various clinical, biochemical and cytological methods for assessing the vitamin A status have been widely used but all are unsatisfactory for technical, ethical or public health reasons. The two prevalence criteria defined by the World Health Organization (WHO) for a vitamin A deficiency problem of public health significance are xerophthalmia and serum retinol concentrations. Recently we proposed a prevalence criterion for impression cytology with transfer (ICT) at the level of 50% of ICT results being abnormal. We conducted a cross-sectional survey of the prevalence of vitamin A deficiency and also undernutrition during the dry season in a random sample of 1,259 children (n = 442 for the 2-6 years and n = 817 for the 7-14 years) from a rural area in Senegal. Prevalence was 0 times and 4.2 times the WHO criteria for xerophthalmia and deficient serum retinol levels, respectively in preschool children. Abnormal ICT results were more frequent in preschool than in school children (53.4% versus 21.0%). There was an association between abnormal ICT results and stunting. Vitamin A deficiency was a public health problem in preschool children as assessed by the biochemical criterion (20.9% of serum retinol values under 0.35 mumol/l) or the cytological cut-off (53.4% of abnormal ICT results) but was also found in school children (21.0% of abnormal ICT results).

Adolescent↗
PubMed1992

Annual assessment of the vitamin A and nutritional status of children during two cross-sectional surveys.

The changes in the vitamin A and nutritional status of children from a rural area in Senegal were determined by the same team during two cross-sectional surveys distant from exactly one year. At baseline (T = 0 year) 1,259 children were chosen at random. One year later (T = 1 year), 1,008 children were re-examined. Vitamin A and nutritional status were assessed by clinical and cytological methods, and by anthropometrical indicators for the 1,008 participants, respectively. No signs of xerophthalmia were recorded at T = 0 and T = 1 year. The proportions of children deficient in vitamin A as defined by abnormal cytology and suffering from stunting were similar at these two measuring points. Even though these percentages remained similar at T = 0 and T = 1 year, there existed little movement between the abnormal and normal eye cytology group and the stunted and non-stunted group. Since vitamin A is required for normal growth, we calculated the mean linear gain in height according to the eye cytological changes assessed between the two examinations. We found that mean linear growth increments were higher in the groups of children who remained abnormal or reverted to abnormal cytology than in those who remained normal or reverted to normal cytology.

Adolescent↗
PubMed1991

Prevalence of malnutrition and vitamin A deficiency in the Diourbel, Fatick, and Kaolack regions of Senegal: feasibility of the method of impression cytology with transfer.

The evaluation of the prevalence of ophthalmological diseases and vitamin A deficiency in Senegalese preschool-aged children enabled us to confirm the method of impression cytology with transfer (ICT) and to assess the impact of ophthalmological diseases on the cytological appearance of conjunctival cells. A simplification of the ICT method consisted of transferring cells present on a strip of paper to a glass slide by finger pressure. Harris-Schorr staining of the sample papers confirmed the results obtained by the transfer. Inflammatory trachoma influenced the results of the test. This simple method will prove very helpful for detection of vitamin A deficiency in children in underdeveloped areas.

Child↗
PubMed1991

Prevalence of malnutrition and vitamin A deficiency in the Diourbel, Fatick, and Kaolack regions of Senegal: epidemiological study.

The purpose of our study was to determine the prevalence of protein-calorie malnutrition (PCM), ocular diseases, and vitamin A deficiency in preschool children selected at random in a rural zone of the groundnut belt of Senegal. The prevalence of PCM was 37.1% (95% CI 33.8-40.2%) according to the Waterlow classification, with a majority of stunting, and prevalence of hypovitaminosis A was estimated to be 11.4% (95% CI 9.3-13.5%) by using impression cytology. Furthermore, 19.4% (95% CI 15.8-22.0%) of the children might be defined at risk of deficiency. The prevalence of Bitot's spots was equal to 0.2% (95% CI 0.03-0.9%). A problem of PCM associated with a health-endangering vitamin A deficiency existed.

Anthropometry↗
PubMed1991

Prevalence of malnutrition and vitamin A deficiency in the Diourbel, Fatick, and Kaolack regions of Senegal: a controlled study.

Two hundred and six Senegalese preschool children included in an epidemiological study were selected by their results from impression cytology with transfer (ICT) for assessment of their nutritional state by means of biological variables and for assessment of the diagnostic values of the ICT. A problem of protein-calorie malnutrition existed (transthyretin and retinol-binding protein concentrations were low) associated with vitamin A deficiency (retinol concentrations were low). The sensitivity and specificity of the ICT defined with respect to retinol (threshold fixed at 0.35 mumol/L) varied with the classification criteria of ICT and seemed to be fairly insensitive but specific.

C-Reactive Protein↗
PubMed1991

[Tonometric results and complications of trabeculectomy in Black Africa. (Apropos of 170 cases of chronic open angle glaucoma operated on at the Ophthalmologic Clinic of CHU in Dakar)].

Intraocular pressure results and complications of trabeculectomy in Black African. The authors reported in 16 years 170 cases of trabeculectomy in Black African with open angle glaucoma. They observed excellent control of intraocular pressure (84% of normalisation at four years). This compared with others, shows that troubles are less important. All this advantages make that trabeculectomy is the best choice that authors advocate in surgical treatment of open angle glaucoma in our countries.

Chronic Disease↗
PubMed1990

[Dermoid of the cornea. Report of 2 cases of Ida Mann's 2nd type].

At the opposite of epibulbar dermoids (which are isolated or combined), dermoids of IDA MANN's second type are uncommon. The two cases reported had a big size and covered almost the cornea, without damage on the descemet's membrane, the endothelium and the other eyeball structures. This lesion is classified by the W.H.O. among choristomas. It's made of skin recovering fat which includes in different figures, hair follicle, eccrine and sweat glands. Total excision is the best treatment, but couls become complicated by cornea perforation. It could be followed in some cases by keratoplasty. Amblyopia could go with this malformation.

Cornea↗
PubMed1989

[Ocular side-effects of corticotherapy (analysis of 3 cases)].

Corticosteroids absorbed into the system, or, in particular, used locally, can lead to serious ocular complications often little understood by those who prescribe them. Among the three cases documented, the authors found one cortisone glaucoma, one cortisone cataract, and one associated glaucoma-cataract. General absorption occurred in one case, a nephrotic syndrome. The two other patients received corticosteroid ointment for chronic limbo-conjunctivitis, endemic in the tropics. Rigorous indication, respect for basic prescription laws, and regular supervision, particularly for long-term treatment, is necessary to prevent these iatrogenic accidents.

Adrenal Cortex Hormones↗
PubMed1989

[Fibrous histiocytoma of the orbit].

The authors reported a case, a large orbital fibrous histiocytoma, in a 14 year old girl. They emphasize nosologic problems and histologic aspects of this benign tumor. Because of the localisation and the size of the tumor, a double anterior orbitotomy (superior and inferior) was necessary for complete renoval. Anatomic, functional and esthetic results were satisfactory.

Adolescent↗