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Biomedical subjects

J F Cuendet

Publications and source records attributed to J F Cuendet.

At least 19 recordsLinked to original sources
PubMed1981

[Ophthalmological side effects of lithium (author's transl)].

Among the side-effects due to the psychotropic drugs, one knows the ocular lesions, especially those due to major tranquillizers (f.e. opacities in the cornea and the lens). Ocular examination of 73 patients suffering of affective disorders, and receiving lithium salts during several years showed no significant ocular lesions due to the medication.

Adult↗
PubMed1978

[Eye a symptoms in relapsing polychondritis (author's transl)].

This is a rare auto-immune illness with necrosis of cartilages. Palpebral oedema, conjunctivitis, episcleritis, iridocyclitis and proptosis belong to this syndrom. But the cataracts often described are iatrogenic, due to the intense corticotherapy required. A report is given of one personal observation and discussion of new therapeutical possibilities.

Cataract↗
PubMed1977

Computer-aided teaching in ophthalmology.

Computer-aided teaching is of a growing importance in ophthalmology. The following problems are particularly reviewed: sequential, ramified and tutorial teaching, exercises in simulation and the checking of knowledge. Most of the technical obstacles have now been resolved. The aim of this paper is to overcome some psychological obstacles due to partial ignorance of the subject by most lecturers in our field.

Computer-Assisted Instruction↗
PubMed1975

Modern trends in human genetics.

Every physician is deeply concerned with the tremendous advances in genetics during the last decade. Through 'gene surgery' DNA transplantation on both somatic and germinal tissue is feasible. Thus, genetic determinism is no longer ineluctable. Tissue culture is a tool to avoid cellular degeneration and achieve cellular immortality.Precise chromosome identification allows one to follow transmission from generation to generation, as well as human gene mapping. Through clinical and especially biochemical methods, genetic entities are dissected more accurately. Ecological genetics studies the risk inherent with drugs, radiations, chemicals and a myriad of environmental factors. On the other hand, behavioral genetics tend to specify the part of the genetic set in human behaviour. Computerized programmes are responsible for some significant advances in population genetics. Prenatal diagnosis, newborn screening programmes, heterozygote detection, and so on, and add a new dimension to genetic counseling. Knowing the part of inheritance in retinal affections, our speciality will greatly benefit from these recent advances in genetics.

Amniocentesis↗
PubMed1975

[Genetics and idiopathic retinal detachment].

Study of all patients treated for retinal deteachment at the University Eye Clinic Lausanne from 1960-1971. All secondary detachments as well as 128 purely traumatic, 120 aphakic detachments and juvenile retinoschisis are not included in these statistics. Therefore there remain 802 patients with idiopathic detachments. A family occurrence is recorded in 7,6% of these cases. Bilateral detachment is observed in 25%. If one counts the controlateral degenerescence of the retina, bilaterality ascends to 42%. The disease occurs at an earlier age in cases with a family background. All these factors allow to appreciate the importance of heredity together with even more important peristatic factors. In 24% of cases, high myopia is associated with detachment. In this instance the heredity of detachment identifies itself with the heridity of myopia. This would be due to an autosomal monofactorial gene with variable penetration. Nevertheless in most cases, the detachment occurs independently of myopia. For the few hereditary cases (3,7%) the detachment or its predisposition would be due to a different gene, but also to a monofactorial autosomal dominant gene with variable and lower penetration, reaching even recessivity, acting together with peristatic often preponderant factors. Several pedigrees of high myopia as well as isolated retinal detachment are presented. Statistics beginning in 1960 do not allow any conclusion on Favre' or Wagner's diseases.

Adult↗
PubMed1975

[Phakomatoses. Ophthalmological and genetic aspects].

Detailed ophthalmological and genetic studies on the four classical types of phacomatoses and more succint studies of twelve syndromes which can be considered as atypical forms of phacomatoses. Discussion of the association between the different forms of phacomatoses. Establishment of genetic prognoses.

Arteriovenous Malformations↗