Biomedical subjects
J F Kurfees
Publications and source records attributed to J F Kurfees.
Drug interactions in the elderly.
Polypharmacy and its dangers in the elderly are of increasing concern. The purpose of this study was to determine the incidence of drug with drug, drug with food, and drug with alcohol interactions in a population aged 60 years or greater. Four hundred patients were randomly selected from a university family medicine outpatient clinic population of 4,483 in this age group. A total of 292 drugs were involved for a total of 1,052 potential interactions: 310 drug-food, 316 drug-alcohol, and 426 drug-drug. Interactions were analyzed using The Drug Master computer program and rated as to their clinical significance. Chart review revealed no serious actual interaction for any patient even though potential interactions could be categorized as highly significant for 27 percent of the drug-drug, 11 percent of the drug-alcohol, and 3 percent of the drug-food. Thirty-two percent of the total population were taking five or more drugs concurrently. The mean number of drugs for men was 3.75 and for women 4.22 (P less than .05). Age and race differences were also noted in the number of drugs taken. The most common drugs and their interactions with drug, food, and alcohol are reviewed.
Acute pancreatitis: pathophysiology and pathogenesis.
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Primary tuberculosis in a 25-year-old man.
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Estimation of the electromotive force of the H+ mechanism of the frog stomach by voltage-clamping.
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Effect of removal of external K+ on frog's stomach in Cl-minus-free solutions.
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Integrating human values in medical education: a physician preceptor program.
The Physician Preceptor Program is a preclinical elective integrating human values into medical education. Through an interdepartmental effort, a one-on-one, mentor-type learning model has been established. Home visits, journal keeping, office visits, and round table discussions are integral components of the course. All participants are enthusiastic about the benefits of the program.