Deep recurrent basal cell epithelioma.
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Biomedical subjects
Publications and source records attributed to J F Leonforte.
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This study is based on clinical findings in 160 patients with skin-limited amyloidosis: 151 macular, 8 biphasic and 1 lichen amyloidosis. 82.5 p. 100 of the patients were women and 17.5 p. 100 were men. 95 p. 100 of the patches were located in the back and 64 p. 100 in the suprascapular region. No less than 88 p. 100 of the patients had pruritus on the patches or on other sites. 75 p. 100 had allergic diseases or a history of allergy, and 45 p. 100 had non-allergic pruriginous diseases. Signs of scratching were noted in most of the patients. The principal causes of pruritus were dermographism, photodermatitis and dermatitis. Macular amyloidosis is now considered as secondary to scratching motivated by pruriginous diseases and not as a primary condition as hitherto described. The term "scratch amyloidosis" is proposed for macular and lichenoid amyloidosis, and the existence of a "preamyloidotic" histological stage is described.
Six men suffering from acute dermatitis had positive patch tests to Larrea (creosote bush). The lesions preferentially involved sun-exposed sites, simulating a photodermatitis, but also were on the legs and scrotum. Our findings were more consistent with contact allergy than with a primary irritant or a phototoxic response. The patch tests were also positive to Zuccagnia punctata. In two cases the exposure to the creosote bush occurred as a result of casual occupations, in two because of household remedies (moist compresses and baths), and in the other two as a result of burning the bush and resorting to household remedies. Attention should be drawn to this contact dermatitis because the creosote bush grows abundantly all over the American continent.
A 15-year-old woman developed an atrophic band on the anterior aspect of her left thigh. A homolateral tibial cyst had been diagnosed five years earlier. To the best of our knowledge, the association of lipoatrophia semicircularis and osseous cysts has, up to now, been unknown.
A typical case of balanitis circumscripta plasmacellularis is described in a 74-year-old man. Electron microscopy revealed a dense infiltrate composed mainly of plasma cells and macrophages; the former showed considerable rough endoplasmic reticulum and phagolysosomes, while the latter contained variable amounts of sideromes. A few mast cells, eosinophils and extravasated erythrocytes were also present. Connective tissue was scarce; no elastic fibres and viral particles were seen.
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Epidermal cysts of the palms and sole of feet are rare. They originate from traumatic implantation of the epidermis into the dermis or subcutis. Three cases (one on the palm and two on the sole of the feet) are reported.
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CNH strongly resembles, both clinically and histopathologically, other lesions showing transepithelial elimination. WE studied 14 cases, only one of which was a woman. Ths lesions had either a smooth surface or a scaly one. Histological findings were rather poor in the smooth lesions; the scaly lesions, instead, which were more advanced, showed epidermal proliferation and perforation, dermal acidophilic necrosis, transepithelial elimination, granulation tissue, and perichondritis. Actinic elastic degeneration seemed to be the first alteration; it was present in all. This, together with the repeated adverse climatic factors and the fact that circulation is of the terminal type in the region affected, is followed by the acidophilic necrosis between the apex of the cartilage and the epidermis. The processes which take place in both cartilage and epidermis are secondary to the dermal lesion. The former perforates and this is followed by elimination of the altered tissues. Persistence of the lesion is to be ascribed to the fact that the diseased cartilage can not be eliminated completely. CNH is the most frequent of the conditions which show transepithelial elimination. It is less frequent in women because they protect themselves from adverse climatic factors by covering their ears with their hair.