PubMed Health⌕ Search

Biomedical subjects

J F Marti-Masso

Publications and source records attributed to J F Marti-Masso.

12 recordsLinked to original sources

Intramedullary spinal sarcoidosis: clinical and magnetic resonance imaging characteristics.

We present a retrospective series of the clinical and MRI findings in 16 patients with intramedullary spinal sarcoidosis (ISS), including 12 patients studied with gadolinium-DTPA. The spectrum of MRI findings includes leptomeningeal enhancement, fusiform spinal cord enlargement, focal or diffuse intramedullary disease, and spinal cord atrophy. We present a classification of ISS correlating the clinical progression and the temporal sequence of MRI abnormalities. Improvement occurred in five of 12 patients (42%) treated with immunosuppressive therapy.

Adult↗

Somatosensory evoked potentials: abnormalities with focal brain lesions remote from the primary sensorimotor area.

Somatosensory evoked potentials (SEPs) were recorded in 41 patients with focal brain lesions recognized by computerized tomography. 21 patients presented damage of the primary sensorimotor area (PSMA), and their SEPs were reduced in amplitude and increased in latency for the two early components (N-22 and N-39), in accordance with previous evidence. The other 20 patients pesented lesions remote from the PSMA, 15 (71%) showing abnormal SEPs mainly characterized by increment in amplitude and duration of N-22 and N-39. Abnormalities of the N-70 and later waves were not specific for any type of lesion. SEPs appeared more sensitive than the EEG for detecting brain dysfunction. The physiopathological and clinical importance of these findings are discussed.

Adult↗

Neurophysiological assessment of alpha pattern coma.

Somatosensory evoked potentials, blink reflexes, and H wave reflexes, were recorded on several days from three patients with alpha pattern coma. Coma was secondary to cardiac arrest in two cases and to brainstem infarction in one. Results are compatible with damage to the brainstem reticular formation with sparing of thalamo-cortical circuits as the main physiopathological characteristic of alpha pattern coma. This condition should not be regarded as a discrete entity when establishing the prognosis of patients in coma, since they only differ from other patients in coma from the point view of the EEG record.

Aged↗

Conduction velocity through the somesthetic pathway in chronic renal failure.

The latencies of evoked potentials recorded at different levels of the peripheral and central nervous system by median nerve stimulation were measured before and after dialysis, and compared with similar recordings in normal volunteers. Abnormally slow conduction velocity was more often found in proximal rather than in distal segments of the peripheral pathway in patients with chronic renal failure. This abnormality was not correlated with the presence of clinical signs of neuropathy or low values of motor conduction velocity, neither was it affected by dialysis. These findings support the hypothesis of peripheral nerve dysfunction secondary to metabolic derangement in uraemic patients.

Adult↗