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Biomedical subjects

J F Mudd

Publications and source records attributed to J F Mudd.

4 recordsLinked to original sources

Aortic aneurysm in childhood: report of six instances.

Six instances of aortic aneurysm in children have been observed in the past 15 years. Four children with aortic stenosis and coarctation of the aorta had aneurysmal dilatation of the ascending aorta, and two children with coarctation of the aorta had ruptured post-stenotic dilatation of the descending aorta. Our observations suggest that aortic aneurysm can be the result of hemodynamic stress, although developmental anomaly of the aorta associated with aortic stenosis or coarctation could be responsible for the development of the aneurysm.

Adolescent↗

Subclavian-coronary artery anastomosis in infancy for the Bland-White-Garland syndrome: a three-year and five-year follow-up.

Two infants, 4 months and 8 months of age, with anomalous origin of the left coronary artery, underwent direct anastomosis of the left subclavian artery to the left coronary artery. In the patient operated upon at 4 months of age, the anastomosis proved to be patent by angiographic study 3 years postoperatively. However, in the patient operated upon at 8 months of age, the study 5 years postoperatively revaled clinically unsuspected occlusion at the anastomosis site. After operation, both patients symptomatically improved. The heart size decreased on radiograms, the left ventricular ejection fraction improved, and the electrocardiographic abnormality resolved to a great extent. Since the preferred treatment for this abnormality and the ideal age for operation are yet to be established, long-term angiographic follow-up of all such surgically treated patients is needed. An advantage of the subclavian-coronary artery anastomosis is its applicability in the infant.

Angiocardiography↗