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Biomedical subjects

J F Pape

Publications and source records attributed to J F Pape.

16 recordsLinked to original sources
PubMed1988

Renal angiography may be used primarily in the diagnosis of renovascular hypertension.

Three hundred and twenty consecutive patients with hypertension were referred to examination with intravenous urography. Only 2 of the 320 urograms performed showed abnormalities possibly related to hypertension. Renal angiography was performed in 39 (12%) of the patients. Seventeen (7%) subjects had renal artery stenosis, of whom 8 (2.5%) were referred to surgery. Four became normotensive and the other 4 had a more treatable hypertension. Urography is an expensive and insensitive method for evaluation of patients with hypertension and should be abandoned. Proper treatment of renovascular hypertension demands the performance of renal angiography. We therefore suggest a program for primary use of renal angiography in the examination of patients with suspected renovascular hypertension.

Adolescent↗
PubMed1987

Intravenous urography in children and youth.

This report derives from Tromsoe in northern Norway. In a retrospective study of the indications for intravenous urography (IU) and the findings at IU in 740 patients (451 girls and 289 boys) aged 0-19 years, we found that urinary tract infections accounted for 69.4% of the IU in females 30.1% of the IU in males, most often seen in the youngest patients. The pathological findings most frequently seen were anomalies (17 females and 10 males) and urinary tract obstruction (3 females and 15 males). The present study indicates the following: first, that the yield of IU in the primary investigation of children and youth suffering from enuresis and non-specific abdominal disturbancies is small; and second, that the use of IU in children and youth with urinary tract infection and haematuria should be questioned and reconsidered.

Adolescent↗
PubMed1986

Intravenous urography and voiding cystoureterography in northern Norway: a retrospective study.

Intravenous urography (IU) was performed in 489 patients aged 0-9 years during 1980-1983. A total of 35 (7.2%), 19 (13.1%) boys and 16 (4.7%) girls had pathological changes at IU. Of these, 11 boys and 5 girls had findings with therapeutic consequences. We have analysed the results of IU and voiding cystoureterography (VC) in 62 patients and show that a normal IU does not exclude vesicoureteral reflux into the renal pelvis. By performing only VC hydronephrosis, pyelonephritic scarring and anomalies may be missed.

Child↗
PubMed1986

A study on oedema mechanism in nephrotic syndrome.

Colloid osmotic pressure in plasma (COPp) and interstitial fluid (COPi), plasma volume (PV) and interstitial fluid volume (IFV) were measured in 14 patients with hypoproteinaemia due to glomerulonephritis and in five healthy controls. In controls, COPp averaged 24.2 mmHg and COPi 12.0 mmHg. In patients with COPp above 12 mmHg, COPi was reduced nearly identical to the fall in COPp. The transcapillary COP gradient (COPp-COPi) was maintained, and PV and IFV were unchanged. When COPp was reduced below 12 mmHg, the transcapillary COP gradient was decreased. Both IFV increased and renal fluid retention occurred. This study demonstrates the relationship between COPp, transcapillary fluid transport, and renal fluid retention in nephrotic syndrome.

Adolescent↗
PubMed1978

Glomerulonephritis in dermatitis herpetiformis. A case study.

A patient with dermatitis herpetiformis, proteinuria and reduced renal function is described. A renal biopsy studied by light and immunofluorescence microscopy revealed a glomerulonephritis with deposits of predominantly IgA and complement C3. Deposits of IgA and C3 were also demonstrated in a biopsy from normal skin, and a common pathway for the skin and renal lesions is suggested.

Complement C3↗