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Biomedical subjects

J F Patterson

Publications and source records attributed to J F Patterson.

At least 37 records · Page 2Linked to original sources

Akinetic parkinsonism and the catatonic syndrome: an overview.

The importance of considering organic diseases when evaluating catatonic patients is illustrated by two cases of akinetic parkinsonism in which the patients became catatonic, with waxy flexibility. The catatonic syndrome occurs in association with a variety of lesions that may affect any level of the central nervous system from the brain stem to the cerebral hemispheres. A review of Parkinson's disease and a critical reappraisal of the catatonic syndrome are presented.

Adult↗

Distance perception in photographic displays of natural settings.

Distance perception of depicted objects was examined as a function of photographic perspective. 24 subjects viewed slides of outdoor scenes and directly estimated the distances to specified objects. Perspective was manipulated by photographing each scene with lenses of four different focal lengths: 48 mm, 28 mm, 24 mm, and 17 mm. Distance perception along the pictorial depth plane (z-axis) was systematically transformed by changing the photographic perspective: the shorter the focal length of the camera lens, the greater the perceived distance. Perceived distance between objects along the lateral plane (x-axis) was unaffected by changes in lens focal length.

Cues↗

Treatment of chorea gravidarum with haloperidol.

Treatment of a case of severe chorea gravidarum with haloperidol is presented. A possible neuropharmacologic explanation of the beneficial effects of the neuroleptics, particularly haloperidol, is offered based on the dopamine antagonism of these drugs. Heightened dopaminergic activity in the striatum is postulated as the basis for the chorea. Indications for the use of haloperidol in chorea gravidarum are discussed.

Adolescent↗

Combined cortical thickness and bone density determination by photon absorptiometry.

Bone cortical thickness and density were measured in rat femurs in vitro by a photon absorptiometry technique. A scan perpendicular to the long bone axis using photons from highly collimated 109Cd or 125I sources yielded the bone wall thickness and attenuation at mid-shaft. A second scan after the bone was rotated axially 90 degrees was taken to measure the wall or shaft thickness identically responsible for the mid-shaft attenuation of the first scan. The mid-shaft attenuation of the second scan was due to the bone thickness derived from the first scan; thus two complementary measurements are derived by this technique. The bone density is then directly calculated with an estimated accuracy of 10% (coefficient of variation) using empirically determined mass attenuation coefficients. Measurements of mass attenuation coefficients of ashed and dried samples were compared with calculated coefficients for estimated bone composition. Results indicate that the mass attenuation coefficient for bone in vivo can be well estimated such that bone density can be accurately derived from this technique.

Animals↗