[3H] Corticosterone binding activity of adrenal incubation media in response to in vivo and in vitro ACTH stimulation.
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Adrenal Glands↗
Biomedical subjects
J F Pritchett
Publications and source records attributed to J F Pritchett.
Interaction of aging with in vitro adrenocortical responsiveness to ACTH and cyclic AMP.
In vitro adrenal accumulation of cyclic 3'5'-adenosine monophosphate (cyclic AMP) and release of corticosterone in response to adrenocorticotropic hormone (ACTH), cyclic AMP or theophylline was assessed in 60- and 340-day-old male rats. Adrenal tissue from mature animals secreted significantly smaller quantities of corticosterone in response to ACTH, theophylline or cyclic AMP. Additionally, mature tissue accumulated significantly less cyclic AMP after treatment with ACTH or a combination of ACTH and theophylline. The data suggest an age-related refractoriness of adrenal cortical tissue to ACTH which may in part be related to decreased availability of and/or sensitivity to cyclic AMP.
Adrenal Cortex↗
Noise stress and in vitro adrenocortical responsiveness to ACTH in wild cotton rats, Sigmodon hispidus.
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Adrenal Glands↗
TSH, theophylline and cyclic AMP: in vitro thyroid activity in aging rats.
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Aging↗
Thyroid and sarcoplasmic reticulum function in halothane-sensitive swine.
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Adenosine Triphosphate↗
Effect of jet aircraft noise upon in vitro adrenocortical response to ACTH in feral Mus musculus.
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Adrenal Glands↗