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Biomedical subjects

J F Santos

Publications and source records attributed to J F Santos.

At least 19 recordsLinked to original sources
PubMed2006

[Short form 36 health questionnaire in hemiplegic patients 2 years after stroke].

INTRODUCTION: Many studies show that subjects with sequelae after stroke have a worse health perception in western societies. Due to the shortage of papers on the Spanish population in this regard, a study was carried out to assess health perception in hemiplegic patients 2 years after stroke in comparison with that of the general population and correlate health perception with demographic, clinical and functional variables. METHODS: Cross-sectional study of 212 community stroke survivors. The main variables collected were: health perception assessed with the Short Form 36 (SF-36), disability assessed with the motor Functional Independence Measure (FIM) and Geriatric Depression Scale (GDS). Statistical tests used: chi2, Student t test and Spearman correlation coefficient. RESULTS: In comparison with the Spanish general population, health perception in hemiplegic male stroke patients is diminished in all areas. In hemiplegic female patients, physical function is the only subscale significantly affected in all age groups. Variables related to worse health perception are: presence of depression, dependence and the belief of the need for kind of social support, A significant correlation was observed between SF-36 values and the motor FIM (r = 0.737 with physical function) and the GDS (r = -0.821 with mental health). CONCLUSIONS: Health perception in hemiplegic patients 2 years after stroke is diminished in comparison with that 348 of the general population. Factors which determine worst health perception are depression, motor dependence, need of caregiver assistance and need of social support.

Activities of Daily Living↗
PubMed2001

Efficacy, safety and predictive factors of therapeutic success with sildenafil for erectile dysfunction in patients with different spinal cord injuries.

STUDY DESIGN: Multicenter, open, prospective, before-after study. OBJECTIVE: To assess the efficacy and safety of sildenafil therapy for erectile dysfunction in patients with spinal cord injury, and the association between the response to sildenafil and factors such as causes and levels of spinal cord injury, grade of ASIA deficit, time since injury, orgasmic perception, and degree of baseline erection. SETTING: Homes of outpatients of 16 spinal cord injury units in Spain. METHOD: One hundred and seventy patients with erectile dysfunction secondary to spinal cord injury, from whom baseline data were collected on their sexual function, and who started treatment with sildenafil 50 mg. An efficacy assessment was made by the patient and his partner, and the score of the International Index of Erectile Function (IIEF) was recorded. RESULTS: It was reported by 88.2% of the patients and 85.3% of their partners that treatment with sildenafil had improved their erections, regardless of the baseline characteristics of the spinal cord injury and erectile function. In responders, this improvement was confirmed by an increase from 12.5 to 24.8 points (P<0.001) of the Erectile Function Domain of IIEF. A significant improvement was also seen in patients' satisfaction with sexual activity and general satisfaction derived from sexual life. Preservation of orgasmic perception and a baseline degree of erection of 3 or 4 (P=0.006) were predictors of therapeutic success. No serious adverse events occurred. CONCLUSION: Sildenafil is an effective, well-tolerated treatment for erectile dysfunction caused by spinal cord injury, regardless of the cause, neurological level, ASIA grade, and time since injury. SPONSORSHIP: Spanish Society of Paraplegia.

Adult↗
PubMed1998

Microleakage of a universal adhesive used as a fissure sealant.

PURPOSE: To evaluate the microleakage of a universal hydrophilic adhesive (OptiBond dual-cure) by itself as a pit and fissure sealant compared to that of an ionomeric product (VariGlass) and two hydrophobic sealants (Delton and Fluroshield). MATERIALS AND METHODS: Sixty-four extracted human third molars were sealed with one of these four materials under either a conventional procedure (free of humidity) or after contamination of the etched surfaces with 3 microliters of human plasma. The sealed teeth were subjected to 1,500 thermocycles (1 min/5-55 degrees C) and to 450,000 mechanical cycles under an 8.5 kgf average load at 37 degrees C. The tooth crowns were partially coated with nail varnish, immersed in a 50% aqueous solution of AgNO3 for 2 h in darkness, washed and then developed for 8 h under fluorescent light. The teeth were sectioned and dye penetration was scored according to a 4-point scale by four trained professionals. RESULTS: An ANOVA suggested that under no humidity conditions, the average score for VariGlass (1.92 +/- 0.36) was significantly higher (P = 0.0006) than that corresponding to the three remaining materials (1.28 +/- 0.20) which were considered equivalent. Under humid (plasma contaminated) conditions, there was complete loss of Delton and Fluroshield in all cases, whereas the average score for VariGlass (1.98 +/- 0.36) was slightly higher (P = 0.0444) than that for OptiBond (1.62 +/- 0.36). These results suggest that OptiBond may be used by itself as a pit and fissure sealant instead of the combination of adhesive plus sealant.

Acrylic Resins↗
PubMed1997

The influence of a mineralizing mouthrinse on the mineral contents and on the pH of dental plaque.

The main objective of this study was to evaluate the effects of a single use of a mineralizing mouthrinse on dental plaque pH and on its mineral contents: an additional objective was to examine the effects of an oral prophylaxis and scaling on the same response variables. A total of 22 volunteer dental students (14 female and 8 male) participated in the study. The mineralizing mouthrinse contained calcium, phosphate, strontium and fluoride ions. Following a 48-hour period without oral hygiene and 2 hours after breakfast, dental plaque was collected twice from each participant for the evaluation of the effects of the oral prophylaxis and scaling, and twice more for the evaluation of the effects of the mineralizing mouthrinse. The pH was measured in vitro with a microelectrode and the mineral contents were determined by atomic emission spectrometry. The results demonstrate that the average post-prophylaxis pH was higher than the average pre-prophylaxis pH, and that a variation of the average contents of some minerals in the dental plaque was also observed after prophylaxis compared to the contents prior to prophylaxis. Although there was a significant reduction in the Fe content after the rinse with the mineralizing solution, no significant variation on the average pH was detected.

Adolescent↗
PubMed1995

Clinical behavior of repaired amalgam restorations: a two-year study.

Replacement of amalgam restorations may lead to more destruction of sound dental tissue, is often a time-consuming chair procedure, and it does not always provide a favorable risk/benefit balance for the patient. This article reviews the clinical alternative of repairing instead of completely replacing old amalgam restorations. During a 2-year period, 45 repaired restorations were monitored every 6 months by direct (clinical) and indirect (color slides and stone casts) methods. Findings of this study reveal broad clinical success when based on proper indications.

Dental Alloys↗
PubMed1994

Heat shock changes the response of the pso3 mutant of Saccharomyces cerevisiae to 8-methoxypsoralen photoaddition.

A putative tolerance, induced by heat shock (HS), to the lethal and mutagenic effects of 8-methoxypsoralen (8-MOP) photoaddition and hyperthermia was analyzed in Saccharomyces cerevisiae using the wild-type strain N123 and the isogenic DNA repair-deficient mutant pso3-1. In wild-type cells, the HS (38 degrees C for 1 h) did not modify either the survival or the mutation frequency observed after 8-MOP photoaddition, even though it conferred protection against the lethal effect of hyperthermia (50 degrees C). In the pso3-1 mutant, HS induced an increase of the survival, and a decrease of the mutation frequency, after 8-MOP photoaddition and it also protected against the lethal effect of hyperthermia. The responses induced by HS were specific for 8-MOP photoaddition, since they were not observed after 254 nm ultraviolet-light damage. These results indicate that the protection conferred by HS depends of the type of lesion, and operates through the induction of different repair processes. In the pso3-1 mutant, HS could channel the repair intermediates to and error-free repair pathway.

DNA Repair↗
PubMed1994

Imaging methods in the study of urinary tract infections in children.

UNLABELLED: When studying a child with urinary tract infection it is important to detect and localize any renal (scar) or urologic anomaly. Here we study the information obtained using: renal and vesical ultrasound (US), DMSA scan and radiologic or isotopic cystogram. METHODS: We studied 148 children with more than one urinary infection and/or pyelonephritis; their mean age was 35.9 months (1-148 months); 55% were girls. The three diagnostic examinations--US, DMSA scan and cystogram were made in this order; the DMSA scan or cystogram was never made sooner than one month after the UTI. RESULTS: In 42% of the children the three exams were normal; 4 of these children had another UTI and the urodynamic study revealed vesical disfunction. 11% had renal scars (DMSA scan) with normal US and cystogram; 30% had VUR, 50% of which had an altered US and 57% had renal scars on the DMSA scan. 12% of the children had an altered US with a cystogram showing no VUR; 66% of these had renal scars. 4% had vesical anomalies in the US and cystogram. CONCLUSION: The three exams chosen were able to direct the diagnostic approach of UTI, being sufficient in most of the cases. We would like to emphasize the importance of the DMSA scan in diagnosing unsuspected renal scars.

Acute Disease↗
PubMed1994

[Computerized tomography of the child's thorax. Clinical use].

The authors describe the use of Computed Tomography for the evaluation of pediatric patients, with a variety of chest diseases. Indications and technical factors are described according to the experience of the examinations done in the first 100 children studied in the Radiology Department of the Santa Maria Hospital.

Child↗
PubMed1993

[Imaging methods in the study of urinary tract infections in children].

UNLABELLED: When studying a child with urinary tract infection it is important to detect and localize any renal (scar) or urologic anomaly. Here we study the information obtained using: renal and vesical ultrasound (US), DMSA scan and radiologic or isotopic cystogram. METHODS: We studied 148 children with more than one urinary tract infection and/or pyelonephritis; their mean age was 35.9 months (1-148 months); 55% were girls. The three diagnostic examinations--US, DMSA scan and cystogram were made in the order; the DMSA scan or cystogram was never made sooner than one month after the UTI. RESULTS: In 42% of the children the three exams were normal; 4 of these children had another UTI and the urodynamic study revealed vesical disfunction. 11% had renal scars (DMSA scan) with normal US and cystogram; 30% had VUR, 50% of which had an altered US and 57% had renal scars on the DMSA scan. 12% of the children had an altered US with a cystogram showing no VUR; 66% of these had renal scars. 4% had vesical anomalies on the US and cystogram. CONCLUSION: The three exams chosen were able to direct the diagnostic approach of UTI, being sufficient in most of the cases. We would like to emphasize the importance of the DMSA scan in diagnosing unsuspected renal scars.

Child↗
PubMed1992

Biologic esthetic restorations.

Cases of serious coronal destruction were treated by bonding parts of extracted teeth to the coronal remnants by means of adhesives and photo-activated composite resins. The long-term clinical results have revealed very satisfactory clinical performance of the compounded restorations. No detrimental effects have been identified.

Child↗
PubMed1989

Interdisciplinary issues in mental health and aging.

An Interdisciplinary Conference on Mental Health and Aging held in Washington, D.C. in May 1986 restimulated the interdisciplinary cooperation generated by the 1980 White House Mini-Conference on the Mental Health of Older Adults and provided a continuing basis for interdisciplinary promotion of coordinated geriatric mental health services. The Conference reflected a wide-spread recognition of the need for interdisciplinary cooperation and the coordination of services for the elderly. The overall organization of the meeting is provided here and articles based on the presentations given by representatives of the four core mental health disciplines follow.

Aged↗
PubMed1984

Community mental health and the elderly: service and training approaches.

There is a growing gap between needed and available mental health services for older adults. This article discusses the training needs, personnel shortages, and lack of effective service programs and proposes some strategies for dealing with the problems. There is a lack of adequate methods for identifying and referring frail elderly persons in need of mental health services. Services that are currently available to the elderly are identified along with factors that may influence their use by older adults and other service personnel. There are shortages of mental health professionals with special training and experience in gerontology and geriatrics, and clinical geropsychologists. An innovative and practical service model that was developed to coordinate and integrate the identification and treatment of frail, community-dwelling elderly is presented. Various aspects of the program that include outreach and case management approaches, the integration of student volunteer activities with those of special volunteer corps within public housing and specially trained paraprofessionals, telephone reassurance programs, and a system of layered supervision are described. Comparisons are made between this Coordinated Agency Resources for Elderly Services (CARES) model and existing service delivery programs. A three-tiered approach to training and coordinating the activities of trained mental health personnel: (a) paraprofessionals and volunteers, (b) middle-level professionals and (c) supervisory professionals within an integrated system is proposed. Specific roles and functions of personnel at each level are described. The summary discusses the potential of the proposed strategies for dealing with the problems created by the shortage of personnel and services. It suggests some time frames within which the strategies could be operationalized.

Aged↗
PubMed1982

Changing patterns in methods of suicide by race and sex.

Suicide rates vary greatly by sex and race but the methods employed by these groups and changes in those methods have been studied neither closely nor systematically across time. In the present study annual official national statistics for specific methods of suicide by sex and racial group from 1923 to 1978 were examined. During this time period shifts were found among groups in the proportions of various suicide methods employed, most notably for women and Asian-Americans. Generally, firearm use increased among nearly all ethnic/racial-sex groups while the use of poisons declined. Although women continue to be more likely than men to kill themselves with solid and liquid poisons, in very recent years firearms have become a more common method. Among Japanese- and Chinese-Americans of both sexes the most frequently employed method has been hanging. Although this is still the case, the proportions have declined over time while the use of firearms has increased. Explanations are offered for the noted changes in method choice with particular attention being given to acculturation and changing societal roles.

Black or African American↗