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Biomedical subjects

J F Seeger

Publications and source records attributed to J F Seeger.

71 records · Page 4Linked to original sources

Vertical fracture of the odontoid: CT diagnosis.

A patient with a vertically oriented fracture of the odontoid is described. We found no previous report of this type of fracture. In our patient CT was the best imaging modality for defining the anatomic extent of the fracture.

Adult↗

Computed tomography in hematologic malignancies of paranasal sinuses.

Hematologic malignancies of the paranasal sinuses are uncommon. Four young patients with ophthalmologic abnormalities as a chief complaint are presented. Lymphoma or leukemia should be considered in the differential diagnosis of destructive lesions in the paranasal sinuses, particularly in children and young adults.

Adult↗

Digital subtraction angiography. Comparison of meglumine-Na diatrizoate with iohexol.

A slight improvement in image quality occurred with the use of iohexol when compared with meglumine-Na diatrizoate. There is less swallowing with iohexol, which gives better image registration when looking at the extracranial carotid arteries. A single significant tachycardia occurred with the ionic medium, but not with iohexol. Overall discomfort and minor adverse reactions were less with iohexol than with diatrizoate.

Adult↗

High-dose i.v. contrast in CT scanning of the postoperative lumbar spine.

Evaluation of the postoperative lumbar spine is sometimes difficult because of obliteration of epidural fat by hypertrophic scarring. We examined 70 patients using a high-dose intravenous contrast technique in an attempt to distinguish hypertrophic scarring from herniated disk. The CT interpretation was confirmed in all 17 patients who had follow-up operations. Thirteen had herniated disk material associated with scar and four had hypertrophic scarring only. The latter four patients underwent reoperation because of concomitant foraminal or spinal canal stenosis seen on CT. Twelve of the herniated disks had the expected appearance of a nonenhancing mass surrounded by a rim of enhancing scar tissue. In the 13th patient, homogeneous enhancement of the herniated disk was seen. It is thought that chronically herniated disks, such as this one, may incite enough surrounding scar to give the CT appearance of an enhancing disk. Finally, marginal enhancement in the anulus fibrosus region was seen in over 90% of disk spaces examined. Although an anatomical explanation cannot be given at present, this phenomenon is thought to represent a normal finding.

Adult↗

Conventional vs computed radiography: evaluation of myelography.

A prospective study was performed to compare the diagnostic efficacy of conventional film-screen (FS) imaging with computed radiography (CR) in myelography. Forty examinations were done with both methods. Digital myelography was found to have diagnostic accuracy equal to that of conventional film-screen examinations.

Diagnosis, Computer-Assisted↗

Digital subtraction angiography of glomus tympanicum and jugulare tumors.

Radiologic procedures used to evaluate patients with suspected glomus tumor have included plain skull radiography, temporal bone tomography, computed tomography, and cerebral angiography. Of these, only angiography has proven reliable as a screening procedure for small glomus tympanicum and jugulare tumors. Digital subtraction angiography was used as the initial examination for suspected paraganglioma in 14 patients. Intravenous digital subtraction angiography proved to be an acceptable screening tool for these highly vascular tumors. Also, intraarterial digital subtraction angiography proved very satisfactory for mapping of tumor blood supply, which greatly simplified preoperative embolization. Effectiveness of therapy was readily ascertained by serial follow-up intravenous digital subtraction angiography.

Adult↗

Evaluation of cerebral hemispheric contrast transit with intravenous digital subtraction angiography.

Thirty-six patients with varying degrees of stenosis of one internal carotid artery were studied using intravenous digital subtraction angiography, assessing relative hemispheric washin and washout of contrast medium. Ipsilateral delayed contrast transit was seen in 16 of 18 patients with a 70% or greater carotid artery stenosis. Decreased hemispheric peak contrast density was also seen in most of these patients. With further improvements in the computer program and faster imaging rates, intravenous digital subtraction angiography has the capability of providing valuable physiologic data along with anatomic information in patients with suspected cerebral ischemia.

Aged↗

Carotid-cavernous sinus fistulas and venous thrombosis.

Radiographic signs of cavernous sinus thrombosis were found in eight consecutive patients with an angiographic diagnosis of carotid-cavernous sinus fistula; six were of the dural type and the ninth case was of a shunt from a cerebral hemisphere vascular malformation. Diagnostic features consisted of filling defects within the cavernous sinus and its tributaries, an abnormal shape of the cavernous sinus, an atypical pattern of venous drainage, and venous stasis. Progression of thrombosis was demonstrated in five patients who underwent follow-up angiography. Because of a high incidence of spontaneous resolution, patients with dural-cavernous sinus fistulas who show signs of venous thrombosis at angiography should be followed conservatively.

Adult↗

Intra-arterial BCNU chemotherapy for the treatment of malignant gliomas of the central nervous system: a preliminary report.

We treated six patients with unilateral malignant astrocytomas with pulse doses of intra-arterial BCNU (200 mg/m2 initially, with escalating doses every 6-8 weeks) via transfemoral selective internal carotid catheterization. Four patients had had partial resections without prior radiation therapy and received no steroids. They had decreased tumor stain and surrounding edema after two to four cycles of chemotherapy. For one patient, results of the neurologic examination returned to normal, with total disappearance of her tumor as assessed by computerized tomographic scan. Objective tumor response continued for 7 months in three patients and for 3 months in one. In two of the four patients, chemotherapy was discontinued because of retinal toxicity and not because of treatment failure. Two patients had had partial resections and radiation therapy. One patient had stable disease for 4 months, and the second had progressive disease with gradual visual loss beginning in the infused eye 3 weeks after the second treatment. The catheterization procedure is safe; it was without immediate complication in 17 BCNU infusions. In summary, high-dose intra-arterial BCNU is well-tolerated and is an effective initial chemotherapeutic modality.

Adult↗