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Biomedical subjects

J F Sherman

Publications and source records attributed to J F Sherman.

15 recordsLinked to original sources

Pituitary adenoma.

Pituitary adenoma is the most common intracranial tumor that affects the visual system. A variety of signs and symptoms of disease may be produced, either ocular or endocrine, depending on the type of tumor involved. Nonfunctional pituitary adenomas show no elevation in serum hormone concentration and produce visual symptoms that result from the compression by the tumor mass of adjacent structures. These tumors are more likely to be diagnosed by an ophthalmic clinician than functional adenomas, which cause endocrine dysfunction and are more likely to be diagnosed by an endocrinologist. Diagnostic imaging and clinical laboratory testing may be used to confirm the presence of the tumor. Treatment for pituitary adenoma includes medication, radiotherapy, surgery, or a combination of these options.

Adenoma

Headache.

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Headache

Shaping national science policy: some lessons learned.

Thirty-five years of experience have taught several lessons about shaping science policy. Derived from these lessons are four premises that deserve individual and collective thought: (1) The partnership in U.S. society between health and science interests is fundamentally important; (2) Scientific merit must be the paramount basis for allocating whatever research funds are available; (3) Better data and their careful analysis are vital to the decision-making processes; and (4) More than ever we must have a clear, concise, vigorous, and repeated enunciation of the principles that are essential for a national biomedical research program to flourish. The fourth premise is expressed succinctly in the 11 principles outlined in the 1983 AAMC monograph "Preserving America's Preeminence in Medical Research," which places important responsibilities for the collective success of the U.S. research program on all of the various components of society. Three important factors favor efforts to shape a useful, successful science policy: a public that places improvements in health high on every priority list, a rapidly expanding body of invaluable knowledge, and a sizable investment of tax-derived funds, now totalling over $7.5 billion per year.

Humans

The organization and structure of the national institutes of health.

In the assessment of domestic federal programs and the agencies responsible for them, few have been as frequently and highly praised as the National Institutes of Health (NIH). Contributing to that success in part is an unusual organization and structure. Based on a series of semiautonomous, disease-oriented program divisions supplemented by several support units with a co-ordinative function performed by the Director, NIH, a remarkable and essential combination of administrative stability and flexibility, as well as scientific and political acceptability, has emerged. The changing environment in which NIH now functions, however, suggests the need for a greater degree of intra-NIH and extra-NIH program integration and co-ordination. Concomitantly, there must be more consistent federal policies, a clearer definition and understanding of "technology transfer" and additional resources for the directors of NIH and the individual Institutes.

Financing, Government