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Biomedical subjects

J F Simeone

Publications and source records attributed to J F Simeone.

At least 109 records · Page 6Linked to original sources

Pancreatitis-associated fluid collections involving the spleen: sonographic and computed tomographic appearance.

The clinical and radiographic features of 2 patients with dissecting pancreatitis-associated fluid collections involving the spleen are described. A typical appearance of left upper quadrant fluid collection lateral to the splenic pulp was observed by ultrasonography (US) or computed body tomography (CBT). Although these findings are nonspecific, a left upper quadrant fluid collection may be characterized definitively by US/CBT-guided needle aspiration.

Acute Disease↗

The value of the left apical cap in the diagnosis of aortic rupture: a prospective and retrospective study.

The authors conducted a prospective and retrospective study of the radiographic findings in 45 patients with traumatic rupture of the aorta. In 7 cases, a left apical cap was the only clearly visible abnormality. In 11 cases a cap was present together with a poorly defined aortic knob, while in 13 cases both were seen along with mediastinal widening. In 14 cases, all of the classical signs of aortic rupture were present, but an apical cap was not seen or was not considered significant. Of 32 aortograms obtained, 12 were taken solely because of an apical cap; 2 were positive for aortic rupture and 10 were negative. No aortic rupture was found in patients with a left apical cap and fractures of the ribs, vertebral bodies, or scapulae.

Accidents, Traffic↗

Postcholecystectomy bile duct dilatation: myth or reality?

Postcholecystectomy dilatation of the common duct has been a matter of controversy in the surgical, radiographic, and sonographic literature. In this study, 40 patients who had biliary sonography before cholecystectomy and were asymptomatic 6 months or more after surgery were returned for sonography of the biliary ducts. Of these, 38/40 showed no evidence of postcholecystectomy dilatation of the common duct. There was diminution of the common duct in one and enlargement in another patient. One patient had a duct that was dilated before surgery and remained the same size after surgery. It is concluded that postcholecystectomy dilatation of the common bile duct does not occur in most normal patients.

Adult↗

Tissue core biopsy of abdominal tumors with a 22 gauge cutting needle.

Percutaneous needle sampling of malignant tumors carried out by fine-needle cytologic aspiration and large-needle cutting techniques both possess certain limitations. A fine caliber 22 gauge cutting needle and a modified sampling technique used in 78 patients with suspected abdominal neoplasms are described. Both cytologic and histologic samples were sought in each case and overall successful diagnoses were made in 88% of 50 proved cases, with specific histologic diagnoses in 56%. Cytologic specimens were more sensitive in 14 cases in the detection of malignancy, while histologic results were more specific in nine cases. No significant complications were encountered. This modified method has not replaced the former cytologic aspiration technique in this institution.

Abdominal Neoplasms↗

Triangulation method for percutaneous needle guidance: the angled approach to upper abdominal masses.

A method for percutaneous biopsy and aspiration of posteriorly located retroperitoneal, adrenal, renal, and hepatic masses using computed tomographic or sonographic guidance of an angled needle was used on 17 occasions in 16 patients. The technique uses the Pythagorean theorem for right triangles, and tangent ratios to provide an extrapleural, extraperitoneal route in the prone position for otherwise inaccessible lesions. The more precise geometric planning reduced time to complete the procedure and avoided the complication of pneumothorax which had been previously encountered. Needles were accurately positioned in all patients, and a positive diagnosis was achieved in 13 (three patients had intrahepatic hemangiomas and there was one false-negative necrotic carcinoma).

Abdominal Neoplasms↗

Appearance of lymphomatous involvement of the mesentery by ultrasonography and body computed tomography: the "sandwich sign".

A characteristic appearance of lymphomatous involvement of the mesentery is demonstrated by ultrasonography and computed tomography. The presence of a lobulated confluent mass infiltrating the mesenteric leaves and encasing the superior mesenteric artery and veins producing a "sandwich-like" appearance is reported in seven patients with Hodgkin and non-Hodgkin lymphoma. Retroperitoneal adenopathy was present in all seven patients. In six, a correct prospective diagnosis was made and a major revision of therapeutic planning occurred. Laparotomy was deferred in three patients. The anatomy, pathophysiology, and clinical importance are detailed.

Adult↗

Significance of nonshadowing focal opacities at cholecystosonography.

Nonshadowing focal opacities within the gallbladder lumen are a frequent finding with cholecystosonography. This study describes a prospective analysis of 125 patients with this finding. In 36 patients surgical proof was obtained. It was found that nonshadowing echogenic foci in the gallbaldder can be separated into two distinct categories and that the incidence of gallstones can be determined for each. The categories are (a) nonshadowing echogenic foci less than 5 mm in size (incidence of gallstones is 81% for those patients coming to surgery) and (b) a fluid-fluid level or sludge (incidence of gallstones is less than 10% for those coming to surgery).

Cholelithiasis↗

Diagnosis of abdominal malignancy by radiologic fine-needle aspiration biopsy.

Fine needle aspiration biopsy in 100 consecutive patients with suspected abdominal malignancy yielded a positive diagnosis in 69 (82%) of 84 patients in cases ultimately proven to have cancer in the area sampled. Of 21 pancreatic cancers, 18 (86%) were detected; 24 (83%) of 29 liver lesions, usually metastases, were identifed; and 16 (78%) of 22 retroperiteonal masses, most frequently metastatic lymph nodes, were correctly diagnosed. Overall success rate for epithelial malignancy was 67 (85%) of 79 and far exceeded the yield in lymphomatous masses where two (40%) of five cases were detected. Several radiologic guidance methods were used including computed body tomography in 41%, ultrasonography in 45%, and fluoroscopy with or without conventional contrast agents in 14%. Complications were negligible. In a subgroup of 20 patients in whom a positive diagnosis was obtained, separate analysis of the cytologic specimen revealed that the first needle pass contained definitive material in 15 (75%) of 20 cases. The results confirm the effectiveness, safety, and wide applicability of fine-needle aspiration biopsy for nonsurgical confirmation of advanced or unresectable intraabdominal malignancy.

Abdominal Neoplasms↗

Clinical efficacy of computed body tomography, II.

The contribution to diagnostic understanding and therapeutic decision making by computed body tomography (CT) was measured in 623 patients using prospective and retrospective inquiry of referring physicians. CT improved diagnostic understanding in 52% of patients, reassured the physician about previously planned therapy in 43%, improved precision of previously planned treatment in 23%, and contributed to a change in therapy in 14%. There was a significant increase over time in reports of improved diagnostic understanding which was probably related to increasing clinical experience with the technique. However, this improvement in diagnostic understanding did not correspondingly increase the frequency of beneficially altered therapy. CT contributed to a substantial decrease in preplanned invasive imaging tests and a decision not to perform surgery in 19% of patients in whom an operation had been previously planned. The value of a CT examination to patient care varied considerably with the clinical problem; the most consistent contributions were observed in patients with diseases suspected in the mediastinum and retroperitoneum.

Attitude of Health Personnel↗

Computerized tomography in the assessment of diseases of the thorax: a critical review.

Many diseases of the chest wall, heart, mediastinum, pleura, and lungs can be successfully imaged by CT. Radiotherapy ports can be calculated and transcutaneous biopsies can be monitored. In future, it is conceivable that by studying the numerical data within these areas of diseased and healthy lung it may be possible to more closely correlate pulmonary function with radiographic images. It is hoped that lung volumes extravascular lung water, blood flow patterns, and many more physiological parameters may become open to elucidation by CT.

Adult↗

Detection of metastatic malignant melanoma by chest roentgenography.

The latest premortem chest roentgenogram on 17 patients with known metastatic malignant melanoma was examined and the results were compared with the findings in the chest at autopsy. In nine of the 17, disease not visible on the roentgenogram was found at autopsy. Preliminary data would indicate that a significant number of these metastases could have been identified premortem by other radiographic modalities, e.g., tomography.

Adult↗

Computerized tomography in the assessment of diseases of the thorax.

Many of the diseases of the chest wall, heart, mediastinum, pleura and lungs can be successfully imaged by computerized tomography. Radiation therapy ports can be calculated and transcutaneous biopsies monitored. This paper deals with the many uses that we have had for computerized tomography in assessing diseases within the chest and thorax.

Adult↗