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J F Towers

Publications and source records attributed to J F Towers.

11 recordsLinked to original sources

Primary epithelioid sarcoma of the hard palate. A case report.

A case of primary epithelioid sarcoma of the hard palate is described with no evidence of metastases. Review of the literature revealed no other reported cases of epithelioid sarcoma at this site. The patient, a 20-year-old male negro, returned with 2 local recurrences after initial excision but with no evidence of metastases. He remains well with no evidence of disease at present. This report records a unique primary site for this tumour, and illustrates the diagnostic difficulties, both clinical and histological, which this tumour may present.

Adult

The primordial cyst (odontogenic keratocyst): its tumour-like characteristics and behaviour.

The clinical behaviour of primordial cysts frequently mimics that of benign tumours. They are characterised by aggressive growth and a tendency to recur following surgical treatment. Displacement of teeth, resorption of the roots of teeth, 'seeding' of the cyst into soft tissue and pathological fracture of the mandible exemplify this behaviour. These features are described and fully illustrated by examples from a series of 60 cases. The results of various surgical procedures are evaluated.

Adolescent

What is Gorlin's syndrome? The diagnosis and management of the basal cell naevus syndrome, based on a study of thirty-seven patients.

A series of 37 patients with Gorlin's syndrome is described; 23 had the typical naevi, 19 had jaw cysts and only 10 had both. A wide range of associated deformities was noted. The need for early identification of patients at risk is stressed; follow-up is essential for 2 reasons: The naevi although indistinguishable histologically from basal cell carcinomas only rarely require radical removal. The jaw cysts are locally invasive and should be radically removed when small. In 8 patients examined there was a low level of alpha-globulins in the plasma. Spontaneous involution of the naevi may occur in un-irradiated skin.

Adolescent

Maxillary sinusitis mimicking malignant disease.

The diagnostic features of both maxillary sinusitis and neoplastic disease of the antrum are described. In most cases the clinical and radiographic evidence will lead to the correct diagnosis. However, in the two cases presented here, the clinical and radiographic evidence of neoplastic disease of the maxillary sinus was not confirmed by biopsy and histologic examination. The significant fact that radiographic evidence of bone destruction of the antral walls can occur in maxillary sinusitis is discussed. This sign, together with a unilateral epistaxis, must always be considered as evidence of neoplastic disease of the maxillary sinus. Where there is any doubt, biopsy must be performed.

Aged