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Biomedical subjects

J F Val Bernal

Publications and source records attributed to J F Val Bernal.

At least 19 recordsLinked to original sources
PubMed2001

[Leydig cell tumor. Report of 2 cases and review of the literature].

The Leydig cell tumor is the most frequent of non-germ cell tumors of the testis. Clinical findings depend on the age of presentation. We present two cases of Leydig Cell tumors of the testis, diagnosed in a 8 years old child with isosexual precocity, and a 42 years old adult with Gynaecomastia. After reviewing the existing literature on this uncommon pathology we consider that the iconography presented is very interesting for furthering the knowledge on this subject.

Adult↗
PubMed1994

[Experimental renal transplantation of cirrhotic donors. I. Morphologic, immunofluorescence, and ultrastructural study].

The cirrhotic kidney can be successfully transplanted into healthy recipients. The histological lesions have not been well defined or correlated with the functional changes observed in cirrhosis. Methods to induce experimental cirrhosis in the rat that reliably reproduce this disease have been developed. The development of microsurgical techniques have made it possible to perform transplantation in the rat. We analyzed the renal lesions of cirrhotic rats and the evolution of the graft after transplantation into a healthy rat.

Animals↗
PubMed1994

[Experimental renal transplantation of cirrhotic donor. II. Stereologic analysis].

Cirrhotic nephromegaly is accompanied by an important glomerular growth that progress to glomerulosclerosis and is irreversible and independent of the initial cause. The deterioration of renal function in these patients following liver transplantation and in chronic cirrhotics may be secondary to glomerular sclerosis, also known as "hepatic glomerulosclerosis". We utilized stereologic methods to quantify the volumetric changes in cirrhotic rats, fundamentally the glomerular changes, before and after transplantation into healthy rats. We had initially intended to look for terminal cirrhotics that were potential kidney donors; however, currently many of these can be liver graft recipients. In our view, our findings can be applicable to these patients since the kidney is removed from a cirrhotic and transplanted into a healthy environment, as in our experiment.

Animals↗
PubMed1985

[Epidemiology of colorectal carcinoma in Cantabria].

Colorectal cancer is increasing due to both a real increase and a better diagnosis. More cases are seen in men than in women (ratio 1.45). The incidence increases with age, reaching the highest point at 75 years of age in men and at 84 years of age in women. Before 50 years of age, the risk of colorectal cancer is higher in women; the contrary happens after this age. Colorectal cancer is localized in the rectum (47.5%), sigmoid flexure (25.3%) and coecum (8.1%). Synchronous colorectal carcinomas are seen in 2.3% of the patients, frequently coexisting with multiple adenomas, and show a tendency to be localized out of the rectum. A higher proportion of carcinomas localized in the descending colon and a diminution of rectum carcinomas are observed in men with increasing age, while in women the number of carcinomas of the ascending colon increases and that of the descending colon decreases. For the considered period (1970-81), a diminution of the ascending colon carcinomas has been registered.

Adult↗
PubMed1985

[Global prognosis and stage classification of colorectal carcinoma].

A study on the life prognosis of patients with carcinoma of the colon and rectum is made. 393 patients are studied, 90% of which were followed up during five years or until their death. The authors indicate the classification of stages they have followed with good correlation results, and without overlapping of the survival calculations for the different subgroups.

Colonic Neoplasms↗
PubMed1985

[Gastric carcinoma in Cantabria: I. Incidence and distribution].

We have proceeded to study the rate of incidence and distribution in Cantabria of six hundred and thirty two patients suffering from gastric carcinoma in a period of time ranging from 1970 to 1981. The rate of incidence being observed among this population amounts to 14.54, cases per one hundred thousand inhabitants and year between 1976-1981. This rate increases with age in women more than in men. We have also been able to see how those cases where the carcinoma has appeared at an early age, under thirty, concern females exclusively. Males have been affected by this pathology more than females in a proportion of 1.38:1. We have verified there exists a special geographical distribution of this kind of tumour in our region, being Reinosa the judicial district presenting the highest rate of incidence.

Adolescent↗
PubMed1985

[Gastric carcinoma in Cantabria: II. Histopathological aspects].

In this study we have proceeded to analyze the differences found in each histological type of gastric carcinoma according to age and sex, showing a predominance of tubular adenocarcinoma in advanced ages, affecting females, as an average, more than males. We have also found out how other histological types such as the signet ring cell adenocarcinoma tend to appear at an early age, concerning females preferably. We have also checked on the pathogenesis concerning the different histological types described by certain authors as to age and sex.

Adenocarcinoma↗
PubMed1985

[Gastric carcinoma in Cantabria: III. Anatomo-pathological factors of prognostic significance].

In the present study, we have proceeded to analyze different anatomo-pathological parametres concerning 638 gastric carcinomas, for a twelve year period between 1970-1981, such as location and macroscopic aspect, tumoral extension and histological type, observing their prognosis in the case of curative surgery. We have also proceeded to analyze the rate of survival amounting to 5 years in all the patients being examined, depending on the therapeutical attitude in use. We then proceeded to compare our series with others already published, thus coinciding in the best prognosis as to tumoral location in antrum-pylorus with an ulcerated aspect, less depth as to intraparietal invasion, as well as an absence of ganglionar compromise and visceral metastasis. We also proceeded to analyze the rate of survival concerning the histological type, according to WHO classification.

Humans↗