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J FABRICANT

Publications and source records attributed to J FABRICANT.

16 recordsLinked to original sources
PubMed1963

RESPIRATORY PATHWAYS IN THE MYCOPLASMA. I. LACTATE OXIDATION BY MYCOPLASMA GALLISEPTICUM.

Smith, S. L. (Cornell University, Ithaca, N.Y.), P. J. Van Demark, and J. Fabricant. Respiratory pathways in the Mycoplasma. I. Lactate oxidation by Mycoplasma gallisepticum. J. Bacteriol. 86:893-897. 1963.-Resting cells of Mycoplasma gallisepticum 293 required the addition of nicotinamide adenine dinucleotide, thiamine pyrophosphate, and flavine mononucleotide for the maximal rate of sodium lactate oxidation. Inhibitor studies, as well as spectrophotometric and chemical assays, indicate that the pathway of electron transport to oxygen during lactate oxidation does not involve heme catalysts, and is mediated by flavin-linked enzyme systems. The presence of reduced nicotinamide adenine dinucleotide-specific lactic dehydrogenase, menadione reductase, ferricyanide reductase, and reduced nicotinamide adenine dinucleotide oxidase activities was detected in cell-free extracts. No cytochrome c reductase or reduced nicotinamide adenine dinucleotide peroxidase activity was detected in these extracts.

Adenine Nucleotides↗
PubMed1962

Primary isolation of Mycoplasma organisms (PPLO) from mammalian sources.

Barber, T. L. (Cornell University, Ithaca, N.Y.) and J. Fabricant. Primary isolation of Mycoplasma organisms (PPLO) from mammalian sources. J. Bacteriol. 83:1268-1273. 1962.-Mycoplasma (PPLO) were isolated from cattle, pigs, sheep, rats, and dogs. A total of 39 isolates was obtained from 307 samples from 166 animals. Of these, 24 isolates were from semen of bulls in an artificial breeding establishment; the other 15 were from various tissues of the animals mentioned. Variations of two basal media together with chicken embryos were used in primary isolation attempts. PPLO enrichment broth (Difco) was supplemented with either horse or swine serum. The broth was used as overlay with a horse blood agar slant. Viande foie (VF) medium was usually enriched with horse or swine serum and was used both with and without 1% yeast hydrolyzate. Chicken embryos (5 days old) were inoculated via the yolk sac. Of the 39 isolations made, 22 were obtained on a single variation of one basal medium or only after a passage through chicken embryos. The 22 were isolated as follows: 4 in modified PPLO enrichment broth; 13 in variations of VF medium; and 5 were found only after growth in chicken embryos. The other 17 isolates grew, on primary culture, in a combination of media. Only three of these grew in all media and in embryos. Eight grew in two variations of VF basal, two in both VF and PPLO enrichment broths, one in embryos and PPLO enrichment broth, and three in embryos, and VF basal medium. If either basal medium or chicken embryos had been omitted from the trial, many isolations would not have been made.

Animals↗
PubMed1958

Heat stroke.

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Heat Stroke↗